O-methylcatechol
SMILES:
COc1ccccc1O
Aroma Description:
phenolic, smoky, spicy, vanilla, woody, medicinal, savory, meaty1
Receptor | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
---|---|---|---|---|
OR10G4 | -7.7 6 | 10 6 | vanilla, carnation, smoky | |
OR10G7 | -6 2, -2.4 3 | 8.1972 2, 5 3 | clove, carnation, smoky | |
OR1G1 | - | 5.3299 4 | waxy, tart, orange, sweet, aldehydic, medicinal, citrus, clean, fresh, anise | |
OR10G9 | -2.49 3 | 3.75 3 | (insufficient data) | |
OR52D1 | - | 1.269 4 | anise, cheesy, rancid, orange, dairy, sour, sweet, tart, sharp, pineapple | |
OR7D4 | - | 0.3 5 | animal |
O-methylcatechol
SMILES:
COc1ccccc1O
Aroma Description:
phenolic, smoky, spicy, vanilla, woody, medicinal, savory, meaty
Receptor | Docking Score | Correlated Perceptual Qualities |
---|
1.) The Good Scents Company
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
3.) C. Trimmer, A. Keller, N. R. Murphy, L. L. Snyder, J. R. Willer, M. H. Nagai, N. Katsanis, L. B. Vosshall, H. Matsunami, and J. D. Mainland Genetic variation across the human olfactory receptor repertoire alters odor perception PNAS | May 7, 2019 | vol. 116 | no. 19 | 9475–9480
4.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
5.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.
6.) J.D. Mainland, A. Keller, Y.R. Li, T. Zhou, C. Trimmer, L.L. Snyder, A.H. Moberly, K.A. Adipietro, W.L.L. Liu, H. Zhuang et al, The missense of smell: functional variability in the human odorant receptor repertoire, Nat. Neurosci. 17 (2014) 114-120