Olfactory Receptor family 2 subfamily A member 7.
Sequence:
10 20 30 40 50 60 70 80 90 100 MGDNITSITE FLLLGFPVGP RIQMLLFGLF SLFYVFTLLG NGTILGLISL DSRLHAPMYF FLSHLAVVDI AYACNTVPRM LVNLLHPAKP ISFAGRMMQT 110 120 130 140 150 160 170 180 190 200 FLFSTFAVTE CLLLVVMSYD LYVAICHPLR YLAIMTWRVC ITLAVTSWTT GVLLSLIHLV LLLPLPFCRP QKIYHFFCEI LAVLKLACAD THINENMVLA 210 220 230 240 250 260 270 280 290 300 GAISGLVGPL STIVVSYMCI LCAILQIQSR EVQRKAFCTC FSHLCVIGLF YGTAIIMYVG PRYGNPKEQK KYLLLFHSLF NPMLNPLICS LRNSEVKNTL 310 KRVLGVERAL
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 I R P G L G A F S L L I H T D P G Q E K P L M Q N V L M M R V L H I N E N V Y M I Y K K L G F L M R P V L F T Q L S L A L V M I A T F L L L L S F T N C T S F L V G T I A G G Y F L L S H F V Y F A Y A I T V A F T W S V L G S G I V M P N F L L T D V V L C E T V A L L P G C L H S P N L T G N G A L H S V V L L T I C V I T S F C T S C I L G L I L F F Y S M V R W T Y S V C F A K L S I L Y M P A V Y L D L I C M R Q V C I A I A C E R S Q H Q L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| lilial | -4.96 1 | 6.7857 1 | floral, muguet, watery, green, powdery, cumin | |
| alpha-pinene | -4.39 1 | 6.7857 1 | camphoraceous, earthy, fresh, pine, sweet, woody | |
| beta-pinene | -4.34 1 | 4.2857 1 | dry, green, hay, pine, resinous, woody | |
| lauric acid | -4.82 1 | 3.3571 1 | bay, coconut, fatty | |
| tert-butylbenzene | -4.19 1 | 2.8571 1 | ||
| caprylic acid | -4.82 1 | 1.4286 1 | cheesy, fatty, oily, rancid, vegetable, waxy | |
| cyclohexyl salicylate | -3.05 2 | 1.75 2 | floral, balsamic, sweet, green | |
| 3-phenylbutyraldehyde | - | 0 1 | foliage, green, herbal, hyacinth |
1.) Emily A. Yasi, Sara L. Eisen, Hanfei Wang, Widianti Sugianto, Anita R. Minniefield, Kaitlyn A. Hoover, Paul J. Branham, and Pamela Peralta-Yahya Rapid Deorphanization of Human Olfactory Receptors in Yeast Biochemistry 2019, 58, 2160-2166
2.) Tsai T, Veitinger S, Peek I, Busse D, Eckardt J, Vladimirova D, Jovancevic N, Wojcik S, Gisselmann G, Altmüller J, Ständer S, Luger T, Paus R, Cheret J, Hatt H. Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation. Exp Dermatol 26: 58 - 65, 2017. doi:10.1111/exd.13132