Olfactory Receptor family 4 subfamily E member 2.
Sequence:
10 20 30 40 50 60 70 80 90 100 MDSLNQTRVT EFVFLGLTDN RVLEMLFFMA FSAIYMLTLS GNILIIIATV FTPSLHTPMY FFLSNLSFID ICHSSVTVPK MLEGLLLERK TISFDNCITQ 110 120 130 140 150 160 170 180 190 200 LFFLHLFACA EIFLLIIVAY DRYVAICTPL HYPNVMNMRV CIQLVFALWL GGTVHSLGQT FLTIRLPYCG PNIIDSYFCD VPLVIKLACT DTYLTGILIV 210 220 230 240 250 260 270 280 290 300 TNSGTISLSC FLAVVTSYMV ILVSLRKHSA EGRQKALSTC SAHFMVVALF FGPCIFIYTR PDTSFSIDKV VSVFYTVVTP LLNPFIYTLR NEEVKSAMKQ 310 320 LRQRQVFFTK SYT
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 L V R N L L N D F S T L L Y T D P R I S F S L M E G E L T I C F T Q G I G T T Y I F V K D A M F F M K P V F F L Q L S H T V I L I C P F V S V A S F T V S L H L V T G G G S N G F F L V T Y L M Y I S H C I A C A F L W L L S I T A V V L P T V S L T D I F F I E A F V L F C S M F H A P N L L I N G S L N S I I L L Q I C V V A L S C T T Y I F I I I L F F Y A V V R M N Y S T S L A K V T A Y M P T V Y R D L I V M Q R G C I A L S V E A S H T K R UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| n-amyl acetate | -3 1 | - | banana, fruity, solvent, sweet, apple, ethereal, pear | |
| geraniol | - | 1.9231 2 | citrus, floral, fruity, rose, sweet, waxy | |
| 3-phenylpropionic aldehyde | - | 1.9231 2 | fresh, cortex, green, leafy, foliage, balsamic, storax, aldehydic, floral, melon | |
| 2,4,6-trichloroanisole | - | 1.9231 2 | cork_taint |
1.) J.D. Mainland, A. Keller, Y.R. Li, T. Zhou, C. Trimmer, L.L. Snyder, A.H. Moberly, K.A. Adipietro, W.L.L. Liu, H. Zhuang et al, The missense of smell: functional variability in the human odorant receptor repertoire, Nat. Neurosci. 17 (2014) 114-120
2.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).