SMILES:
CC(=CCCC(=CCO)C)C

Aroma Description:
citrus, floral, fruity, rose, sweet, waxy1

Receptor log10 EC50 Adj. Top Antagonist? Correlated Perceptual Qualities
OR1A1 -3.47 5, -8 6 9.7 5, 4.5 7  passionfruit, herbal, orange, caraway, weedy, hay, spearmint, licorice, plastic, mushroom
OR1A2 -8 6 4.5 7  ozone, orange, aldehydic, peel, citrus, spearmint, caraway, rose, green, tart
OR2W1 -8.46 2, -4.74 5 3.5042 2, 9.5 5  sweet, herbal, tart, fatty, orange, passionfruit, fresh, mimosa, rancid, mushroom
OR10A6 -6.48 11 -  floral, cinnamyl, honey, rhubarb, neroli, hyacinth, cyclamen, balsamic, cinnamon, dirty
OR2AG2 -5.74 11 -  cinnamyl, hyacinth, cinnamon, floral, rose, balsamic, neroli, blueberry
OR2M7 -3 2, -3.2 5 0.5427 2, 8 5  eggy, cabbage, alliaceous, garlic
OR2W3 - 8.1395 10  lemon, citrus
OR1D2 -4 8 -  rose, peach, bois_de_rose, citrus, floral, fresh, lactonic, coconut, lime, waxy
OR1G1 - 6.599 4  waxy, tart, orange, sweet, aldehydic, medicinal, citrus, clean, fresh, anise
OR4C3 -2.7 2 1.1127 2  currant, plum, rose
OR4X2 -2.46 2 1.2152 2  grape
OR4E2 - 1.9231 12  solvent, storax, cork_taint, cortex, pear, foliage, ethereal, banana, apple
OR10S1 - 1.5 3  watery, cilantro, orange_peel, cumin, orris, aldehydic, greasy, muguet
OR52D1 - 0.7614 4  anise, cheesy, rancid, orange, dairy, sour, sweet, tart, sharp, pineapple
OR10J5 - 0 5   
OR2C1 - 0 5   
OR2J2 - 0 5   
OR51E1 - 0 5   
OR51L1 - 0 5   
OR5A1 - 0 9   
OR5A2 - 0 9   
OR5AN1 - 0 9   
OR11H4 - 0 11   
OR5I1 - 0 12   
OR2L13 - 0 15   
OR5P3 - 0 5, -0.4065 13   
OR8H1 - -0.4065 13   
OR5K1 - -0.1626 13, -0.5714 14   

SMILES:
CC(=CCCC(=CCO)C)C

Aroma Description:
citrus, floral, fruity, rose, sweet, waxy

Receptor Docking Score Correlated Perceptual Qualities

1.) The Good Scents Company

2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.

3.) Emily A. Yasi, Sara L. Eisen, Hanfei Wang, Widianti Sugianto, Anita R. Minniefield, Kaitlyn A. Hoover, Paul J. Branham, and Pamela Peralta-Yahya Rapid Deorphanization of Human Olfactory Receptors in Yeast Biochemistry 2019, 58, 2160-2166

4.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002

5.) Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD. Odor coding by a Mammalian receptor repertoire. Sci Signal. 2009 Mar 3;2(60):ra9. doi: 10.1126/scisignal.2000016. PMID: 19261596; PMCID: PMC2774247.

6.) Silva Teixeira CS, Silva Ferreira AC, Cerqueira NM. Studying Haloanisoles Interaction with Olfactory Receptors. ACS Chem Neurosci. 2016 Jul 20;7(7):870-85. doi: 10.1021/acschemneuro.5b00335. Epub 2016 May 9. PMID: 27092849.

7.) Schmiedeberg K, Shirokova E, Weber HP, Schilling B, Meyerhof W, Krautwurst D. Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2. J Struct Biol. 2007 Sep;159(3):400-12. doi: 10.1016/j.jsb.2007.04.013. Epub 2007 May 25. PMID: 17601748.

8.) Veithen, A.; Wilin, F.; Philippeau, M.; Chatelain, P. OR1D2 is a broadly tuned human olfactory receptor. Chem. Senses 2015, 40, 262–263.

9.) Keiichi Yoshikawa, Jun Deguchi, Hu Jieying et al. Diverse yet selective tuning of an odorant receptor for sensing four classes of musk compounds, 03 August 2022, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-1916850/v1]

10.) Huang, J., Lam, H., Koziol-White, C., Limjunyawong, N., Kim, D., Kim, N., ... & An, S. S. (2020). The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. Proceedings of the National Academy of Sciences, 117(45), 28485-28495.

11.) Duroux R, Mandeau A, Guiraudie-Capraz G, Quesnel Y, Loing E. A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors. Molecules. 2020 Oct 16;25(20):4743. doi: 10.3390/molecules25204743. PMID: 33081083; PMCID: PMC7587601.

12.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).

13.) Aya Kato, Naoko Saito (2015) Odor control agent. JP5798382B2

14.) Aya Kato, Naoko Saito, Michiaki Inoue, Kayoko Nomizu (2015) Method of identifying an agent for inhibiting odor of pyrazine derivatives US9057090B2

15.) Morrell CN, Mix D, Aggarwal A, Bhandari R, Godwin M, Owens P 3rd, Lyden SP, Doyle A, Krauel K, Rondina MT, Mohan A, Lowenstein CJ, Shim S, Stauffer S, Josyula VP, Ture SK, Yule DI, Wagner LE 3rd, Ashton JM, Elbadawi A, Cameron SJ. Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms. J Clin Invest. 2022 May 2;132(9):e152373. doi: 10.1172/JCI152373. PMID: 35324479; PMCID: PMC9057618.