Olfactory Receptor family 52 subfamily B member 4.
Sequence:
10 20 30 40 50 60 70 80 90 100 MPTVNHSGTS HTVFHLLGIP GLQDQHMWIS IPFFISYVTA LLGNSLLIFI ILTKRSLHEP MYLFLCMLAG ADIVLSTCTI PQALAIFWFR AGDISLDRCI 110 120 130 140 150 160 170 180 190 200 TQLFFIHSTF ISESGILLVM AFDHYIAICY PLRYTTILTN ALIKKICVTV SLRSYGTIFP IIFLLKRLTF CQNNIIPHTF CEHIGLAKYA CNDIRINIWY 210 220 230 240 250 260 270 280 290 300 GFSILMSTVV LDVVLIFISY MLILHAVFHM PSPDACHKAL NTFGSHVCII ILFYGSGIFT ILTQRFGRHI PPCIHIPLAN VCILAPPMLN PIIYGIKTKQ 310 320 IQEQVVQFLF IKQK
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 D Q L G I A L R D L S L I R I D T I C P P M H Q A Q P I T I C F I I P W I N L I T F P I H I S I W T C T F F L Q F I T S F G Y I G S V N A L F F P S L V I S H I G Y S R M L I G Y F L L I C V Y S I D A G S I F T L S V V V T S I I I M P P A L A T A L M C G S E T V C I V D L C V H S P N L S N G L L F L V L L I K K I F I L V G F T G Y I I I L L Y M P E F A M L A N T Y S I N L A K K I L I I F I Y H D L I L M H C A C I A V A H D P S P Y H F UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB 2
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| diacetyl | - | 2.5 1 | buttery, caramellic, creamy, pungent, sweet | |
| geosmin | - | 1.9231 2 | earthy, fresh, musty, soil | |
| 1-octen-3-one | - | 1.9231 2 | earthy, metallic, mushroom | |
| sandranol | - | 1.9231 2 | woody, sandalwood, greasy, oily, waxy | |
| 2,4,6-trichloroanisole | - | 1.9231 2 | cork_taint | |
| delta-decalactone | - | 0.4167 1 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| butyric acid | - | 0 1 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy |
1.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.
2.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).