Olfactory Receptor family 56 subfamily A member 3.
Sequence:
10 20 30 40 50 60 70 80 90 100 MTTHRNDTLS TEASDFLLNC FVRSPSWQHW LSLPLSLLFL LAVGANTTLL MTIWLEASLH QPLYYLLSLL SLLDIVLCLT VIPKVLTIFW FDLRPISFPA 110 120 130 140 150 160 170 180 190 200 CFLQMYIMNC FLAMESCTFM VMAYDRYVAI CHPLRYPSII TDHFVVKAAM FILTRNVLMT LPIPILSAQL RYCGRNVIEN CICANMSVSR LSCDDVTINH 210 220 230 240 250 260 270 280 290 300 LYQFAGGWTL LGSDLILIFL SYTFILRAVL RLKAEGAVAK ALSTCGSHFM LILFFSTILL VFVLTHVAKK KVSPDVPVLL NVLHHVIPAA LNPIIYGVRT 310 320 QEIKQGMQRL LKKGC
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 W S P S I T L A P F S L I T V D L V F V V D P S W H Q V K P I L F C I P I P L H N L L I L V P P L S L V T L I Y M Q L T M A F Q Y T S F F L V N L L S L C L V I C N M L V N R W G G L I L V H H L L F L D L L M A L F T L I G L L T M F H S A A P I G V A S L L S C S E F M A A L D S G C T P N L T T N A L L Y V M F T K V V F I L I S L A K G Y I I M L L Y L P Q Y A M F H D T Y S L A V A V W I T V Y R D L I F T G E A K C I A V A R H R L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| eugenol | -3.97 1 | 0.3351 1 | clove, spicy, sweet, woody | |
| butyric acid | - | 1.6667 2 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| diacetyl | - | 0.6667 2 | buttery, caramellic, creamy, pungent, sweet | |
| delta-decalactone | - | 0 2 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet |
1.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
2.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.