dodecanoic acid
SMILES:
CCCCCCCCCCCC(=O)[O-]
Aroma Description:
bay, coconut, fatty1
| Receptor | Expression | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|---|
| OR51B5 | ? | -5.12 2 | 3.5714 2 | sour, weedy, civet, hay, grassy, cooling, leafy, berry, melon, coconut | |
| OR2A7 | ? | -4.82 2 | 3.3571 2 | pine, cumin, resinous, muguet, hay, watery | |
| OR1G1 | 61 | - | 1.269 3 | sweet, waxy, citrus, fresh, tart, orange, aldehydic, floral, rose, fatty | |
| OR52D1 | 100 | - | 0.0761 3 | dairy, cheesy, anise, milky, creamy, sour, sharp, peach, lactonic, rancid | |
| OR51E1 | 100 | - | 0 4 | ||
| OR51L1 | 88 | - | 0 5 |
dodecanoic acid
SMILES:
CCCCCCCCCCCC(=O)[O-]
Aroma Description:
bay, coconut, fatty
| Receptor | Expr.% | Agonist? | Dock Score | Known agonist | Correlated Perceptual Qualities |
|---|
Dock Score is a measure of how strongly the algorithm thinks the odorant is likely to be an agonist of the receptor.
Receptors in italics are "orphans", i.e. receptors whose agonists have not been identified experimentally.
1.) The Good Scents Company
2.) Emily A. Yasi, Sara L. Eisen, Hanfei Wang, Widianti Sugianto, Anita R. Minniefield, Kaitlyn A. Hoover, Paul J. Branham, and Pamela Peralta-Yahya Rapid Deorphanization of Human Olfactory Receptors in Yeast Biochemistry 2019, 58, 2160-2166
3.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
4.) YOSHIFUMI FUJITA, TOMOKO TAKAHASHI, AKIKO SUZUKI, KAYO KAWASHIMA, FUTOSHI NARA & RYUTA KOISHI (2007) Deorphanization of Dresden G Protein-Coupled Receptor for an Odorant Receptor, Journal of Receptors and Signal Transduction, 27:4, 323-334, DOI: 10.1080/10799890701534180
5.) Roger Emter, Christel Merillat, Fiona Buchli, Felix Flachsmann, Andreas Natsch. Decoding human olfaction by high heterologous expression of odorant receptors detecting signature odorants. Current Biology, October 10, 2025