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Olfactory Receptor family 3 subfamily A member 4.

Estimated Expression: 73% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MDLGNSGNDS VVTKFVLLGL TETAALQPIL FVIFLLAYVT TIGGTLSILA AILMETKLHS PMYFFLGNLS LPDVGCVSVT VPAMLSHFIS NDRSIPYKAC 

       110        120        130        140        150        160        170        180        190        200 
LSELFFFHLL AGADCFLLTI MAYDRYLAIC QSLTYSSRMS WGIQQALVGM SCVFSFTNAL TQTVALSPLN FCGPNVINHF YCDLPQPFQL SCSSVHLNGQ 

       210        220        230        240        250        260        270        280        290        300 
LLFVAAAFMG VAPLVLITVS YAHVAAAVLR IRSAEGRKKA FSTCSSHLTV VGIFYGTGVF SYTRLGSVES SDKDKGIGIL NTVISPMLNP LIYWTSLLDV 

       310        320        330        340        350 
GCISHCSSDA GVSPGPPVQS SLCCLQFTAL LSPPPGWGGL SPLNSHGL

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


D K D S       V   L H V S     L A   P I S R      I F  L A A T  
 I G K   S G L R   Q G N   V T Q T   A K Y    H S L    I P Q   
N L I G   T Y S   V F L L   L A N   E S L C  M A P V  I V F L  
 I V T   F V G T   A A A   T F S F   F F L    T V S    L L F   
L M P S   G Y F   V G M F   V C S   L L H F  V C G V  T V Y A  
 L P N   I G V V   L P A   M G V L   A G A    D P L    G I T   
    Y I   T L H   T I L V   A Q Q   L F C D  S L N G  S L T G  
         S S C T   Y S V   I G W S   I T L    L F F    A L I   
          S F A   A V H A           D Y A M  Y M P S  M L I A  
         K K R G   V A A             L Y R                 E   
                    I R L           Q C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
2-methylisoborneol - 10 1  earthy, musty
bean pyrazine - 3.25 1  green_pea, earthy, beany, chocolate, nutty
2,4,6-trichloroanisole - 2 1  cork_taint
galbanum pyrazine - 0.75 1  green_pea, bell_pepper, green, galbanum

1.) Son, M., D. G. Cho, J. H. Lim, J. Park, S. Hong, H. J. Ko, and Park, T. H. (2015) Real-time monitoring of geosmin and 2- methylisoborneol, representative odor compounds in water pollution using bioelectronic nose with human-like performance, Biosens. Bioelectron., 74: 199–206.

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