Olfactory Receptor family 56 subfamily B member 1.
Sequence:
10 20 30 40 50 60 70 80 90 100 MNHMSASLKI SNSSKFQVSE FILLGFPGIH SWQHWLSLPL ALLYLSALAA NTLILIIIWQ NPSLQQPMYI FLGILCMVDM GLATTIIPKI LAIFWFDAKV 110 120 130 140 150 160 170 180 190 200 ISLPECFAQI YAIHFFVGME SGILLCMAFD RYVAICHPLR YPSIVTSSLI LKATLFMVLR NGLFVTPVPV LAAQRDYCSK NEIEHCLCSN LGVTSLACDD 210 220 230 240 250 260 270 280 290 300 RRPNSICQLV LAWLGMGSDL SLIILSYILI LYSVLRLNSA EAAAKALSTC SSHLTLILFF YTIVVVISVT HLTEMKATLI PVLLNVLHNI IPPSLNPTVY 310 320 330 ALQTKELRAA FQKVLFALTK EIRS
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 S H I G I A L E P L S L P R R D T I L T A H Q W I K P I A F C V P V P I S N L H T L V P L S L W I T T A Y I Q T V F V L Q C V S I V L V N L A L P A L G M F H I L G N R W A L V V I I N H L Y L L D V M M G V F L V M G M G L T Y F F S P P I L A S C L I G G S E F L T A L D S L I L P N L T N A A L F I C L L I K L I I I L S T L H S Y V T L I L Y M P Q F A M L S S T Y S L S C T W I I I V Y R D L I L I S L A K C I A V S Y A A A H R L E A S N UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| diacetyl | - | 2.5 1 | buttery, caramellic, creamy, pungent, sweet | |
| butyric acid | - | 1.6667 1 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| delta-decalactone | - | 1.6667 1 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| hexanal | - | 0.7 2 | aldehydic, fatty, fresh, fruity, grass, green, leafy, sweaty |
1.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.
2.) Ojiro I, Katsuyama H, Kaneko R, Ogasawara S, Murata T, Terada Y, et al. (2024) Enhancement of transcription efficiency by TAR-Tat system increases the functional expression of human olfactory receptors. PLoS ONE 19(6): e0306029. https://doi.org/10.1371/journal.pone.0306029