Olfactory Receptor family 51 subfamily T member 1.
Sequence:
10 20 30 40 50 60 70 80 90 100 MAIFNNTTSS SSNFLLTAFP GLECAHVWIS IPVCCLYTIA LLGNSMIFLV IITKRRLHKP MYYFLSMLAA VDLCLTITTL PTVLGVLWFH AREISFKACF 110 120 130 140 150 160 170 180 190 200 IQMFFVHAFS LLESSVLVAM AFDRFVAICN PLNYATILTD RMVLVIGLVI CIRPAVFLLP LLVAINTVSF HGGHELSHPF CYHPEVIKYT YSKPWISSFW 210 220 230 240 250 260 270 280 290 300 GLFLQLYLNG TDVLFILFSY VLILRTVLGI VARKKQQKAL STCVCHICAV TIFYVPLISL SLAHRLFHST PRVLCSTLAN IYLLLPPVLN PIIYSLKTKT 310 320 330 IRQAMFQLLQ SKGSWGFNVR GLRGRWD
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 C E L G V G L A K F S A I W P K A L V R P V H A V T P L I F C V L L P F S S L S L S T S C I S I W T T I F F M Q L L F F L G W I L P I N A L C V P T L C L A H V V A P R L Q L V Y F I L L Y T Y L C D V A L L S F I C I G N L Y T V A V P P L L A I A L M S S S E V L G I V D T C I H C P N L S N G L L F Y A V L V V L V L I F L V C T S Y I I F I M Y M P K F A M M R D T Y S F S L A K K L I I V L V F R D L I L V Q Q K C I A V T R K R A V N G L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| oranger crystals | -5.15 1 | 4.7059 1 | sweet, neroli, orangeflower, powdery, honey, floral, orange, naphthyl, citrus | |
| (R)-(-)-carvone | -4.4 1 | 5.8824 1 | herbal, minty, spearmint, sweet | |
| (S)-(+)-carvone | -4.46 1 | 5 1 | bready, caraway, minty, spicy | |
| linalool | -4.4 1 | 3.8235 1 | blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody | |
| para-anisaldehyde | -4.52 1 | 2.5882 1 | sweet, powdery, mimosa, floral, hawthorn, balsamic, vanilla, anise, woody, coumarinic, creamy, spicy | |
| (Z)-3-hexen-1-ol | -3.82 1 | 2.3529 1 | fresh, green, grassy, foliage, vegetable, herbal, oily, melon_rind, pungent | |
| delta-decalactone | - | 2.0833 2 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| butyric acid | - | 0.4167 2 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| diacetyl | - | 0 2 | buttery, caramellic, creamy, pungent, sweet | |
| heptanal | - | 0 3 | aldehydic, cognac, fatty, fresh, green, herbal, ozone |
1.) Ieki T, Yamanaka Y, Yoshikawa K (2022) Functional analysis of human olfactory receptors with a high basal activity using LNCaP cell line. PLOS ONE 17(4): e0267356.
2.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.
3.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.