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beta-naphthyl methyl ketone

SMILES:
CC(=O)C1=CC2=CC=CC=C2C=C1

Aroma Description:
sweet, neroli, orangeflower, neroli, powdery, honey, floral, orange, naphthyl, citrus1

Receptor log10 EC50 Adj. Top Antagonist? Correlated Perceptual Qualities
OR1D2 -4.67 2, -3.7 3 2.0588 3  rose, peach, bois_de_rose, citrus, floral, fresh, lactonic, coconut, lime, waxy
OR5P3 -4.2 3 10 3  mimosa, hawthorn, hay, coumarinic, orangeflower, naphthyl, acacia, blueberry, neroli, powdery
OR51T1 -5.15 3 4.7059 3  spearmint, orangeflower, caraway, neroli, blueberry, minty, naphthyl, bois_de_rose, bready, hawthorn
OR2J2 -4.3 3 3.7647 3  tart, carnation, orange, hay, clove, sweet, warm, cinnamon
OR10A6 -4 3 3.2353 3  floral, cinnamyl, honey, rhubarb, neroli, hyacinth, cyclamen, balsamic, cinnamon, dirty
OR8B3 -3.8 3 3.5294 3  orangeflower, neroli, hawthorn, anise, naphthyl, mimosa, spearmint, coumarinic, powdery
OR2W1 -4.4 3 2 3  sweet, herbal, tart, fatty, orange, passionfruit, fresh, mimosa, rancid, mushroom
OR10Q1 -4.2 3 2.3529 3  natural, orangeflower, powdery, neroli, animal, musk, naphthyl
OR11H6 -4 3 2.3529 3  orangeflower, neroli, naphthyl
OR2J3 -4.7 5 0.1889 5  passionfruit, candy, currant, warm, cinnamon, tart, juicy, hay, foliage
OR2S2 -3.8 3 1.1765 3  orangeflower, neroli, carnation, naphthyl, clove
OR8H1 -3.8 3 0.6471 3  naphthyl, orangeflower, spearmint, neroli, carnation, peppery, clove, fecal, smoky
OR1A1 -3.3 3 0.8235 3  passionfruit, herbal, orange, caraway, weedy, hay, spearmint, licorice, plastic, mushroom
OR5A1 - 0 4   
OR5A2 - 0 4   
OR5AN1 - 0 4   
OR5K1 - -0.4571 6   

beta-naphthyl methyl ketone

SMILES:
CC(=O)C1=CC2=CC=CC=C2C=C1

Aroma Description:
sweet, neroli, orangeflower, neroli, powdery, honey, floral, orange, naphthyl, citrus

Receptor Docking Score Correlated Perceptual Qualities

1.) The Good Scents Company

2.) Veithen, A.; Wilin, F.; Philippeau, M.; Chatelain, P. OR1D2 is a broadly tuned human olfactory receptor. Chem. Senses 2015, 40, 262–263.

3.) Ieki T, Yamanaka Y, Yoshikawa K (2022) Functional analysis of human olfactory receptors with a high basal activity using LNCaP cell line. PLOS ONE 17(4): e0267356.

4.) Keiichi Yoshikawa, Jun Deguchi, Hu Jieying et al. Diverse yet selective tuning of an odorant receptor for sensing four classes of musk compounds, 03 August 2022, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-1916850/v1]

5.) Saito N, Yamano E, Ishii A, Tanaka M, Nakamura J, et al. (2018) Involvement of the olfactory system in the induction of anti-fatigue effects by odorants. PLOS ONE 13(3): e0195263. https://doi.org/10.1371/journal.pone.0195263

6.) Aya Kato, Naoko Saito, Michiaki Inoue, Kayoko Nomizu (2015) Method of identifying an agent for inhibiting odor of pyrazine derivatives US9057090B2