terrasol, 6-ethyl-1,5,5-trimethylbicyclo[2.2.1]heptan-6-ol
SMILES:
CC1(C2CCC(C2)(C1(O)CC)C)C
Aroma Description:
camphorous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea1
| Receptor | Expression | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|---|
| OR11A1 | 100 | -5 2, -3.98 3, -9 5, -4.9948 6 | - | patchouli, earthy | |
| OR7D4 | 96 | - | 0.2 4 | animal, citrus, orange, peely, tart, aldehydic, blueberry | |
| OR10G3 | 96 | - | 0 3 | ||
| OR10G7 | 80 | - | 0 3 | ||
| OR10J5 | 84 | - | 0 3 | ||
| OR1C1 | 100 | - | 0 3 | ||
| OR2A25 | 100 | - | 0 3 | ||
| OR2B11 | 100 | - | 0 3 | ||
| OR2J2 | 92 | - | 0 3 | ||
| OR2J3 | 100 | - | 0 3 | ||
| OR51E1 | 100 | - | 0 3 | ||
| OR51L1 | 88 | - | 0 3 | ||
| OR56A4 | 100 | - | 0 3 | ||
| OR5K1 | 100 | - | 0 3 | ||
| OR8K3 | 92 | - | 0 3 | ||
| OR8D1 | 96 | - | -0.0433 3 | ||
| OR2W1 | 53 | - | -1 3 | ||
| OR1A1 | 73 | - | -1.6667 3 | ||
| OR5P3 | 100 | - | -2.3333 3 |
terrasol, 6-ethyl-1,5,5-trimethylbicyclo[2.2.1]heptan-6-ol
SMILES:
CC1(C2CCC(C2)(C1(O)CC)C)C
Aroma Description:
camphorous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea
| Receptor | Expr.% | Agonist? | Dock Score | Known agonist | Correlated Perceptual Qualities |
|---|
Dock Score is a measure of how strongly the algorithm thinks the odorant is likely to be an agonist of the receptor.
Receptors in italics are "orphans", i.e. receptors whose agonists have not been identified experimentally.
1.) The Good Scents Company
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
3.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821
4.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.
5.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.
6.) Lena Ball, Tim Frey, Franziska Haag, Stephanie Frank, Sandra Hoffmann, Matthias Laska, Martin Steinhaus, Klaus Neuhaus, and Dietmar Krautwurst Geosmin, a Food- and Water-Deteriorating Sesquiterpenoid and Ambivalent Semiochemical, Activates Evolutionary Conserved Receptor OR11A1 Journal of Agricultural and Food Chemistry Article ASAP