Olfactory Receptor family 2 subfamily W member 1.

Estimated Expression: 53% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MDQSNYSSLH GFILLGFSNH PKMEMILSGV VAIFYLITLV GNTAIILASL LDSQLHTPMY FFLRNLSFLD LCFTTSIIPQ MLVNLWGPDK TISYVGCIIQ 

       110        120        130        140        150        160        170        180        190        200 
LYVYMWLGSV ECLLLAVMSY DRFTAICKPL HYFVVMNPHL CLKMIIMIWS ISLANSVVLC TLTLNLPTCG NNILDHFLCE LPALVKIACV DTTTVEMSVF 

       210        220        230        240        250        260        270        280        290        300 
ALGIIIVLTP LILILISYGY IAKAVLRTKS KASQRKAMNT CGSHLTVVSM FYGTIIYMYL QPGNRASKDQ GKFLTLFYTV ITPSLNPLIY TLRNKDMKDA 

       310        320 
LKKLMRFHHK STKIKRNCKS 

    

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


G Q D K       R   T T T D     T L   S I T K      W L  M K P H  
 L F K   N G P Q   M E V   T C L V   G V Y    N V L    I M E   
Y F L T   L Y M   A F V S   V S N   Q I I C  M Q P I  V G S L  
 I V T   Y I I T   I G L   A L S I   V Y L    I S T    I A V   
L S P T   G Y F   L V I I   S W I   L W M Y  T F C L  I L Y F  
 L P N   M S V V   L P T   M I I M   V S G    D L F    V L T   
    Y I   T L H   L I L I   K L C   L L C E  S L N R  A T N G  
         S G C T   Y S I   L H P N   V A L    L F F    L I I   
          N M A   A I Y G           D Y S M  Y M P T  L L S A  
         K R Q S   V A K             T F R                 D   
                    T R L           K C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
allyl phenylacetate -8.3 1 9.8 1  honey, fruity, rummy
geraniol -8.46 2 9.5 2  citrus, floral, fruity, rose, sweet, waxy
2-heptanone -7.52 1 9 1  banana, cheesy, coconut, creamy, fruity, green, herbal, ketonic, spicy, sweet, waxy, woody
hexanal -6.52 3 10 3  aldehydic, fatty, fresh, fruity, grass, green, leafy, sweaty
cinnamaldehyde - 10 4  sweet, spicy, candy, cinnamon, warm
1-octanol -6.52 1 9.5 1  aldehydic, green, mushroom, orange, rose, waxy
benzophenone -5.9 5 10 5  balsamic, rose, metallic, powdery, geranium, herbal, plastic, phenolic
benzyl acetate -5.47 6 10 6  sweet, floral, fruity, jasmine, fresh
(Z)-3-hexen-1-ol -5.7 2 9 2  fresh, green, grassy, foliage, vegetable, herbal, oily, melon_rind, pungent, lettuce
coumarin -5.3 1 9.5 1  coumarinic, hay, sweet, tonka
(S)-(-)-citronellol -5.11 6 9.5 6  citrus, fatty, floral, fruity, green, leathery, rose, sweet, terpenic, waxy
furfuryl sulfide -5.406 2 -  
(R)-(-)-carvone -4.66 2 9.7 2  herbal, minty, spearmint, sweet
1-nonanol -5.05 2 9 2  aldehydic, citrus, clean, dusty, fatty, floral, fresh, oily, orange, rose, sweet, tart, waxy, wet
(S)-(+)-carvone -4.65 6 9.5 6  bready, caraway, minty, spicy
(+)-dihydrocarvone -4.76 6 9.3 6  herbal, minty, mentholic
nonanal -5.21 2 8.5 2  waxy, aldehydic, rose, fresh, orris, orange_peel, fatty, peely
hexyl acetate -4.86 2 9 2  apple, banana, fruity, green, sweet
hexanol -4.85 6 9 6  ethereal, fusel, oily, fruity, alcoholic, sweet, green, pungent, apple_skin
1-heptanol -4.83 6 9 6  musty, leafy, violet, herbal, green, sweet, woody, peony, pungent, vegetable, fruity, apple, banana
octanal -5.45 2 8 2  aldehydic, citrus, fatty, green, orange, peel, waxy
3,4-hexanedione -4.78 6 9 6  almond, buttery, caramellic, nutty, toasted
anisyl acetate -5.72 7 7.3529 7  sweet, powdery, balsamic, vanilla, fruity, plum, cherry, tonka, creamy, spicy, coumarinic, licorice
benzyl methyl disulfide -5.141 2 -  
(Z)-2-octenal -5.058 2 -  fatty, nutty
2-hexanone -4.13 6 9.5 6  ethereal
ethyl cinnamate -5.013 2 -  sweet, balsamic, fruity, spicy, powdery, berry, plum, cinnamyl, green
3-octanone -5.02 6 8 6  fresh, herbal, lavender, mushroom, sweet
2-nonanone -4.7 2 8.5 2  fresh, sweet, green, weedy, earthy, herbal, fruity, waxy, soapy, cheesy, coconut, dairy, dirty, buttery
3-octen-2-one - 8 8  earthy, spicy, herbal, sweet, mushroom, hay, blueberry
4-chromanone -4.04 6 9.5 6  
caprylic acid -4.85 6 8.2 6  cheesy, fatty, oily, rancid, vegetable, waxy
capric acid -3.76 2 9.8 2  citrus, fatty, rancid, sour
methyl furfuryl disulfide -4.941 2 0 9  sulfurous, coffee, roasted, alliaceous, meaty, liver, onion, garlic, eggy
dihydrojasmone -4.25 6 9 6  floral, fresh, herbal, jasmine, myrrh, outdoors, spicy, woody
1-octen-3-one -4.902 2 -  earthy, metallic, mushroom
1-decanol -4.37 6 8.5 6  aldehydic, clean, fatty, floral, green, orange, sweet, tart, watery, waxy
pelargonic acid -3.72 10 9.5 10  cheesy, dairy, dirty, waxy
octanethiol -4.03 6 9 6  sulfurous
methyl propyl trisulfide -4.800 2 -  sulfurous, onion, garlic, green, metallic
diallyl disulfide -4.766 2 -  alliaceous, garlic, metallic, onion
nonanethiol -4.06 6 8.7 6  
(E,Z)-2,6-nonadienal -4.718 2 -  cucumber
butyl formate -4.43 6 8 6  fruity, plum, rummy, brandy
caproic acid -4.22 2 8.3333 2  cheesy, fatty, sour, sweaty
2-octanone -4.4 6 8 6  earthy, herbal, natural, weedy, woody
prenyl acetate -4.07 6 8.5 6  sweet, fresh, banana, fruity, jasmine, ripe, heliotrope, balsamic
hexanethiol -5 11 7 11  burnt, fatty, sulfurous, meaty, garlic, roasted, alliaceous, nutty, rubbery, vegetable
beta-naphthyl ethyl ether -5.7 5 5.8333 5  naphthyl, floral, orangeflower, powdery, grape
cuminaldehyde -4.509 2 -  spicy, cumin, green, herbal
(E)-2-nonenal -4.482 2 -  fatty, green, cucumber, aldehydic, citrus, soapy, melon
heptanal -4.06 6 7.8 6  aldehydic, cognac, fatty, fresh, green, herbal, ozone
coffee difuran -5.365 2 5.5 2  cabbage, chicken, coffee, meaty, onion, roasted, sulfurous, cocoa, earthy, fungal, mild, mushroom, nutty
benzyl methyl sulfide -4.385 2 -  
(E,E)-2,4-nonadienal -4.355 2 -  chicken, cucumber, fat, fatty, fruit, green, leaf, melon, tropical, violet, waxy
1-phenylethanethiol -4.197 2 -  
ethyl benzoate -4.191 2 -  starfruit
benzyl ethyl ketone -5.2 7 4.9412 7  earthy, green
(Z)-4-decenal -4.124 2 -  green, musty
ethyl phenylacetate -4.122 2 -  beeswax
(E),(E)-2,4-decadienal -4.111 2 -  oily, cucumber, melon, citrus, pumpkin, nutty, fatty, chicken, fried, chicken_fat, coriander, brothy
gamma-decalactone -4.103 2 -  fresh, oily, waxy, peach, coconut, buttery, sweet
ethyl decanoate -4.096 2 -  apple, brandy, fruity, grape, oily, sweet, waxy
grapefruit mercaptan -4.091 2 -  sulfurous, aromatic, grapefruit, naphthyl, resinous, woody, alliaceous, onion, garlic, tropical
benzyl mercaptan -4.089 2 -  
2-thiophenemethanethiol -4.010 2 -  coffee, sulfurous
(Z)-3-hexen-1-yl acetate -3.977 2 -  
(E,Z)-2,6-nonadienol -3.972 2 -  metallic, cucumber
dipropyl trisulfide -3.942 2 -  sulfurous, alliaceous, onion, green, garlic, tropical
2,3-hexanedione -3.36 6 7 6  buttery, sweet
gamma-nonalactone -3.856 2 0 12  buttery, coconut, creamy, oily, sweet, waxy
furfuryl methyl sulfide -3.845 2 -  
d-limonene -4.95 2 4.3333 2  citrus, orange, fresh, sweet
2-furfurylthiol -3.743 2 -  coffee, sulfurous, burnt
1-cyclohexylethanol -5.23 7 3.5294 7  clean, fresh
alpha-phellandrene -3.708 2 -  citrus, herbal, terpenic, green, woody, black_pepper
raspberry ketone -4.8 7 4.1765 7  berry, floral, jammy, raspberry, ripe, seedy, sweet, woody
para-anisaldehyde -3.628 2 -  sweet, powdery, mimosa, floral, hawthorn, balsamic, vanilla, anise, woody, coumarinic, creamy, spicy
phenethyl alcohol -4.01 7 5.1765 7  floral, rose, dried_rose, sweet, fresh, bready, honey
methyl benzoate -3.584 2 -  starfruit, sweet
2-acetylpyrazine -3.582 2 -  popcorn, roasty
phenethyl acetate -5.82 2 1.9444 2  floral, fruity, honey, rose, sweet, tropical
ethyl caproate -3.511 2 0 12  banana, fruity, green, pineapple, sweet, waxy
cinnamyl alcohol -3.500 2 -  balsamic, cinnamon, cinnamyl, fermented, floral, green, hyacinth, powdery, spicy, sweet
phenylpropyl alcohol -3.469 2 -  sweet, spicy, cinnamyl, floral, hyacinth, balsamic, cinnamon, fruity, honey, winey
styralyl alcohol -3.8 7 5 7  almond, fresh, gardenia, hyacinth, sweet
alpha-terpineol -3.450 2 -  pine, terpenic, lilac, citrus, woody, floral, resinous, cooling, lemon, lime
eucalyptol -3.443 2 -  camphorous, eucalyptus, herbal
(+)-sabinene -3.427 2 -  
piperonal -3.394 2 -  maraschino_cherry, bitter_almond, cherry, tropical, custard, vanilla, spicy, sweet, creamy, cinnamyl
(Z)-4-heptenal -3.364 2 -  fishy
3-mercapto-3-methylbutyl formate -3.358 2 -  catty, blackcurrant
delta-octalactone -3.325 2 -  coconut
3-methyl-2,4-nonanedione -3.317 2 0 12  burnt, caramellic, fruity, hay
2-cyclohexyl ethanol -5.08 7 2.4706 7  cooling, dewy, floral, green, lily, peony, rose, waxy
cis-whisky lactone -3.293 2 -  coconut
myrcene -3.290 2 -  peppery, terpenic, spicy, balsamic, plastic, herbal, woody, rose, celery, carrot
3-ethyl phenol -3.289 2 -  phenolic, leathery
5-methyl guaiacol -3.289 2 -  smoky, clove
(S)-3-mercapto-3-methylhexan-1-ol -5.7 13 1.4 13  passionfruit, currant, blackcurrant, green, fruity
ethyl isobutyrate -3.268 2 0 6  alcoholic, ethereal, fruity, fusel, rummy, sweet
2-methylbutyl acetate -3.243 2 -  sweet, fruity
4-vinylguaiacol -4.4 14 3.3333 14  spicy, clove, carnation, phenolic, peppery, smoky, woody, powdery
(R)-3-mercapto-3-methylhexan-1-ol -5.7 13 1.2 13  passionfruit, currant, blackcurrant, green, fruity
dipropyl disulfide -3.213 2 -  sulfurous, earthy, burnt, onion, green_onion
heptanethiol -4.5 11 3 11  onion, skunk, sulfurous
2-pentylpyridine -5.52 2 (agonist) 2  fatty, tallow, green, bell_pepper, mushroom, herbal
4-vinyl phenol -3.049 2 -  chemical, phenolic, medicinal, sweet, musty, meaty
phenethyl mercaptan -5.45 2 (agonist) 2  rubbery, sulfurous
methyl cinnamate -5.38 2 (agonist) 2  balsamic, cherry, strawberry, sweet
3-methyl-3-mercapto butyl methyl ether -2.971 2 -  catty, blackcurrant
cinnamyl acetate -5.2 2 (agonist) 2  sweet, floral, spicy, balsamic, cinnamon
strawberry glycidate 2 -5.2 15 (agonist) 15  sweet, strawberry, berry, floral, tropical, honey, rose
3-mercaptohexyl acetate -5.14 2 (agonist) 2  floral, fruity, pear, tropical, passionfruit, blackberry, raspberry, blackcurrant_bud
helional - 4.6 9  cyclamen, fresh, green, hay, ozone, watery
citral -4.89 16 1.3065 16  sharp, lemon, sweet, fresh, juicy, lemon_peel, tart, green, citrus, lime, woody, herbal
p-cresol -4.52 17 1.8667 17  phenolic, narcissus, animal, mimosa
oranger crystals -4.4 18 2 18  sweet, neroli, orangeflower, powdery, honey, floral, orange, naphthyl, citrus
ethyl 3-methylthiopropionate -2.817 2 -  sulfurous, metallic, pineapple, fruity, ripe, pulpy, tomato
l-limonene -5 2 (agonist) 2  terpenic, pine, herbal, peppery
(S)-(-)-citronellal -4.68 16 1.2419 16  citrus, clean, herbal
4-methyl acetophenone -4.82 2 (agonist) 2  hawthorn, sweet, mimosa, coumarinic, cherry, acacia
estragole -4.79 2 (agonist) 2  sweet, sassafrass, anise, spicy, green, herbal, fennel, phenolic, minty
(E)-anethole -4.7 2 (agonist) 2  sweet, anise, licorice, mimosa, medicinal, spicy
p,alpha-dimethylstyrene -4.69 2 (agonist) 2  clove, guaiacol, phenolic, spicy, styrene, terpenic
1-octen-3-ol -4.65 2 (agonist) 2  mushroom
(E)-2-heptenal -4.57 2 (agonist) 2  pungent, green, vegetable, fresh, fatty
3-heptanone -4.48 6 (agonist) 6  fatty, fruity, green
ethyl cyclohexanecarboxylate -4.44 2 (agonist) 2  cheesy, fruity, winey
ethyl butyrate -2.530 2 -  cognac, fruit, fruity, juicy, pineapple
skatole -4.82 19 0.2846 19  animal, civet, fecal, naphthyl
acetophenone -4.37 6 (agonist) 6  sweet, pungent, hawthorn, mimosa, almond, acacia, chemical
2-heptanol -4.36 2 (agonist) 2  floral, fresh, fruity, green, herbal, lemongrass, sweet, coconut, dill
gamma-octalactone -4.32 2 (agonist) 2  sweet, coconut, waxy, creamy, tonka, dairy, fatty
indole -4.7 19 0.3252 19  animal, fecal, floral, naphthyl
isoamyl acetate -4.21 2 (agonist) 2  banana, fruity, solvent, sweet
3-methyl-2-hexenoic acid -4.22 13 0.8 13  cheesy, fruity
3,4-dimethoxyphenylacetone -4.23 7 0.5882 7  floral, sweet, woody
pentanethiol - 3.5 11  sulfurous, fatty, roasted, meaty, vegetable
methanethiol -3 11 1.5 11  alliaceous, cabbage, cheesy, creamy, eggy, garlic, meaty, oily, vegetable
eugenyl acetate - 2.5 9  carnation, clove, floral, fresh, malty, spicy, sweet, woody
butanethiol - 2.5 11  sulfurous, garlic, onion, eggnog, coffee, fatty, beefy, roasted, cooked
p-cresyl acetate - 2.2 17  narcissus, phenolic, animal
ethanethiol - 1.5 11  cabbage, onion, sulfurous
isopropanethiol - 1.5 11  brothy, chicken, gassy, meaty, onion, ripe, sulfurous
propanethiol - 1.5 11  cabbage, gassy, sweet, onion
tert-butyl mercaptan - 1.3 11  skunk, sulfurous
thietane - 1 11  sulfurous
methyl salicylate - 0.3333 9  minty, wintergreen
allyl heptanoate - 0 6  sweet, pineapple, fruity, waxy, banana, fusel, cognac, ripe, fermented
allylbenzene - 0 6  
amyl hexanoate - 0 9  sweet, green, fruity, estery, pineapple, apple, pear, fatty, waxy, cognac, melon
l-arabinose - 0 9  
benzene - 0 9  gasoline, phenolic, solvent, cinnamon
1,4-bis(4-vinylphenoxy)butane - 0 5  
butyl butyryl lactate - 0 6  creamy, buttery, buttermilk, dairy, cheesy, fatty, waxy, sweaty, green
(-)-camphor - 0 6  
camphor - 0 6  camphorous
gamma-caprolactone - 0 6  herbal, coconut, sweet, coumarinic, tobacco, creamy, lactonic, green
2-coumaranone - 0 6  
cyclohexanone - 0 6  acetone, minty
beta-damascone - 0 9  berry, currant, floral, fruity, honey, plum, rose, tobacco
decanal - 0 9  sweet, aldehydic, waxy, orange_peel, citrus, floral
dimethyl disulfide - 0 9  sulfurous, vegetable, cabbage, onion, malty, creamy
2,4-DNT - 0 9  
ethyl vanillin - 0 9  sweet, creamy, vanilla, caramellic
ethylphenyl acetate - 0 12  anisic, balsamic, black, chocolate, cocoa, dark, floral, honey, licorice, rose, sweet
eugenol - 0 9  clove, spicy, sweet, woody
fenchone - 0 6  camphorous, earthy, herbal, woody
geranyl acetate - 0 9  floral, rose, lavender, green, waxy, herbal, cooling, oily, soapy, citrus, winey, rummy
4-hydroxycoumarin - 0 6  
linalool - 0 9  blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody
lyral - 0 9  aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody
(1S,2R,5S)-(+)-menthol - 0 9  cooling, mentholic, minty, fresh, sweet, herbal
methyl eugenol - 0 9  carnation, cinnamon, clove, fresh, spicy, sweet, warm
oenanthic acid - 0 6  rancid, sour, cheesy, sweaty, waxy, fermented, pineapple, fruity
2-pentanone - 0 6  sweet, fruity, ethereal, winey, banana, woody, fermented
phenyl acetate - 0 6  phenolic, medicinal, animal, resinous, castoreum, woody, smoky, burnt
(+)-2-phenylbutyric acid - 0 6  
propionic acid - 0 9  acidic, cheesy, pungent, vinegar
quinoline - 0 9  earthy, medicinal, musty, rubbery, tobacco
sotolone - 0 9  sweet, caramellic, maple, sugar, burnt_sugar, coffee, brown_sugar, cotton_candy
terpinyl acetate - 0 9  bergamot, citrus, herbal, lavender, lime
valeric acid - 0 6  acidic, cheesy, fruity, milky, sharp, sour, tobacco
vanillic acid - 0 6  beany, brown, creamy, dairy, milky, phenolic, powdery, sweet, vanilla
allyl cyclohexylpropionate - -0.1626 19  sweet, pineapple, tropical, fruity, candy, waxy, apple, green
citronellal - -0.1626 19  sweet, dry, floral, herbal, waxy, aldehydic, citrus
citronellyl acetate - -0.1626 19  floral, green, rose, fruity, citrus, woody, fruit, tropical_fruit
cyclamen homoaldehyde - -0.1626 19  floral, muguet, lily, green, tropical, oily, greasy, marine, balsamic
2-cyclohexylpropanal - -0.1626 19  natural, fresh, green, dusty, fruity
delta-damascone - -0.1626 19  fruity, sweet, rose, natural, petal, currant_bud, black_currant_bud, tobacco
(-)-alpha-fenchol - -0.1626 19  camphorous, clean, cooling, eucalyptus, green, herbal, minty, piney, woody
hydroxycitronellal - -0.1626 19  floral, green, lily, melon, sweet, tropical, waxy
beta-ionone - -0.1626 19  beeswax, berry, floral, fruity, sweet, tropical, woody, fragrant, sour, acid, vinegar, sharp, pungent
lilial - -0.1626 19  floral, muguet, watery, green, powdery, cumin
7-methoxycitronellal - -0.1626 19  fresh, melon, floral, lily, sweet
muscenone - -0.1626 19  animal, musk, soapy
myraldyl acetate - -0.1626 19  fresh, lily, magnolia, sweet, citrus, freesia, green
tetrahydrogeraniol - -0.1626 19  leathery, musty, plastic, rose, sweet
thymol - -0.1626 19  camphorous, herbal, medicinal, phenolic, thyme
triplal - -0.1626 19  green, aldehydic, leafy, cortex, tart, floral, peely
1-(4-hydroxy-3-methoxyphenyl)butan-2-one - -0.2941 7  ginger, phenolic, spicy, sweet, vanilla, woody
ebanol - -0.4065 19  sandalwood, woody, musk
ethyl linalyl ether - -0.4065 19  floral
exaltolide - -0.4065 19  animal, fruity, musk, natural, powdery
galaxolide - -0.4065 19  floral, musk, sweet
(Z)-3-hexenyl salicylate - -0.4065 19  floral, green, metallic, herbal, balsamic
hexyl salicylate - -0.4065 19  fresh, herbal, orchid, green
(Z)-jasmone - -0.4065 19  woody, herbal, floral, spicy, jasmine, celery
labienoxime - -0.4065 19  currant_bud, blackcurrant_bud, green, grapefruit, herbal, rose, sage
melafleur - -0.4065 19  floral, clean, muguet, ozone, marine, sandy, balsamic
methyl ionone gamma - -0.4065 19  violet, sweet, orris, powdery, floral, woody
methyl jasmonate - -0.4065 19  jasmin, floral, oily, green, petal, greasy, soft
3-(3-propen-2-yl phenyl) butanal - -0.4065 19  ozone, cortex, green, floral, melon
gamma-undecalactone -3.642 2 -0.4065 2  fruity, peach, creamy, fatty, lactonic, apricot, ketonic, coconut
amber butanol - -0.6504 19  woody, amber, ambrette
(-)-ambroxide - -0.6504 19  dry, amber, ambergris, paper, musk, woody, cedar, pine, green, seedy
bourgeonal - -0.6504 19  fresh, watery, floral, cyclamen, sweet
civetone - -0.6504 19  clean, musk, dry, animal, sweet
galbascone - -0.6504 19  fresh, green, galbanum, earthy, weedy, pineapple, narcissus, hyacinth, fruity
globanone - -0.6504 19  animal, balsamic, cloth, dry, floral, laundered, musk, tobacco, waxy
(R,S)-methyl cedryl ketone - -0.6504 19  woody, vetiver, amber, leathery, musk, cedar
myrac aldehyde - -0.6504 19  aldehydic, citrus, floral, greasy, marine
nerolidol - -0.6504 19  floral, green, waxy, citrus, woody, fruity, melon
spicy carbonate - -0.6504 19  spicy, woody, floral, green, herbal
octyl octanoate - -0.6667 9  coconut, oily, fruity
n-amyl alcohol - -0.8333 6  fusel, oily, sweet, balsamic, pungent, fermented, bready, yeasty, winey, solvent
butyric acid - -0.9333 9  sharp, acetic, cheesy, buttery, fruity, dairy, creamy
2-ethyl fenchol - -1 9  camphorous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea
isobutylamine - -1 9  cheesy, fishy
pyrazine - -1.3333 9  pungent, sweet, corn, roasted, hazelnut, barley
propanal - -1.6667 9  alcoholic, cocoa, earthy, nutty, whisky, winey
florhydral - -1.8182 10  floral, green, muguet, linden_flower, lily_of_the_valley, fresh
androstenone - -2.3333 9  animal, musky

1.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.

2.) Franziska Haag, Antonella Di Pizio, Dietmar Krautwurst, The key food odorant receptive range of broadly tuned receptor OR2W1. Food Chemistry 375 (2022) 131680

3.) Ojiro I, Katsuyama H, Kaneko R, Ogasawara S, Murata T, Terada Y, et al. (2024) Enhancement of transcription efficiency by TAR-Tat system increases the functional expression of human olfactory receptors. PLoS ONE 19(6): e0306029. https://doi.org/10.1371/journal.pone.0306029

4.) Fukutani, Y., Koshizawa, T., & Yohda, M. (2021). Application of Vapor Phase Stimulation Method for Screening of Human Odorant Receptors Responding to Cinnamaldehyde. Sensors and Materials, 33(12), 4203-4210.

5.) Jabeen A, de March CA, Matsunami H, Ranganathan S. Machine Learning Assisted Approach for Finding Novel High Activity Agonists of Human Ectopic Olfactory Receptors. International Journal of Molecular Sciences. 2021; 22(21):11546. https://doi.org/10.3390/ijms222111546

6.) Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD. Odor coding by a Mammalian receptor repertoire. Sci Signal. 2009 Mar 3;2(60):ra9. doi: 10.1126/scisignal.2000016. PMID: 19261596; PMCID: PMC2774247.

7.) Pierre Chatelain, Alex Veithen, Francoise Wilkin, and Magali Philippeau Deorphanization and Characterization of Human Olfactory Receptors in Heterologous Cells Chem Biodivers. 2014 Nov;11(11):1764-81. doi: 10.1002/cbdv.201400083. PMID: 25408322.

8.) Motoki Yasunaga, Eiji Takai, Shoji Hattori, Kenji Tatematsu, Shun'ichi Kuroda, Effects of 3-octen-2-one on human olfactory receptor responses to vanilla flavor, Bioscience, Biotechnology, and Biochemistry, 2022;, zbac147, https://doi.org/10.1093/bbb/zbac147

9.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821

10.) Aya Kato, Naoko Saito, Etsuji Wakisaka (2016) Method for searching for malodor control agent, malodor control agent, and malodor control method. US9526680B2

11.) Block, Batista, Matsunami, Zhuang, Ahmed The role of metals in mammalian olfaction of low molecular weight organosulfur compound Nat. Prod. Rep., 2017,34, 529-557

12.) Christiane Geithe, Franziska Noe, Johanna Kreissl, Dietmar Krautwurst, The Broadly Tuned Odorant Receptor OR1A1 is Highly Selective for 3-Methyl-2,4-nonanedione, a Key Food Odorant in Aged Wines, Tea, and Other Foods, Chemical Senses, Volume 42, Issue 3, 1 March 2017, Pages 181–193, https://doi.org/10.1093/chemse/bjw117

13.) Aya Kato, Naoko Saito (2018) Search method for odor control agent JP6422665B2

14.) Aya Namba, Naoko Saito, Keiichi Yoshikawa, Ichiro Mori (2015) Search method of urine odor suppressor JP2015211667A

15.) Ichie Ojiro, Ryusei Kaneko, Takahiro Kashiwagi, Ikuo Terada, Kunihide Hoshino, Yuko Terada, Keisuke Ito, Odorants have the potential to enhance the heterologous expression of human olfactory receptors: evidence from ethyl 3-phenylglycidate and its effects on OR1A1, OR11G2, and OR2W1, Biochemical and Biophysical Research Communications, 2025, 151459, ISSN 0006-291X,

16.) Audouze K, Tromelin A, Le Bon AM, Belloir C, Petersen RK, et al. () Identification of Odorant-Receptor Interactions by Global Mapping of the Human Odorome. PLoS ONE 9(4): e93037. doi:10.1371/journal.pone.0093037

17.) Shirai, T., Takase, D., Yokoyama, J. et al. Functions of human olfactory mucus and age-dependent changes. Sci Rep 13, 971 (2023). https://doi.org/10.1038/s41598-023-27937-1

18.) Ieki T, Yamanaka Y, Yoshikawa K (2022) Functional analysis of human olfactory receptors with a high basal activity using LNCaP cell line. PLOS ONE 17(4): e0267356.

19.) Aya Kato, Naoko Saito (2015) Odor control agent. JP5798382B2

×
 
 

Code version:
 

Docker used:
 

Files:
Active model: text 3D download
Inactive model: text 3D download
Active dock: text 3D download
Inactive dock: text 3D download
JSON entry: text   download