☰

Olfactory Receptor family 4 subfamily X member 2.

Estimated Expression: 53% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MTEFIFLVLS PNQEVQRVCF VIFLFLYTAI VLGNFLIVLT VMTSRSLGSP MYFFLSYLSF MEICYSSATA PKLISDLLAE RKVISWWGCM AQLFFLHFFG 

       110        120        130        140        150        160        170        180        190        200 
GTEIFLLTVM AYDHYVAICK PLSYTTIMNW QVCTVLVGIA WVGGFMHSFA QILLIFHLLF CGPNVINHYF CDLVPLLKLA CSDTFLIGLL IVANGGTLSV 

       210        220        230        240        250        260        270        280        290        300 
ISFGVLLASY MVILLHLRTW SSEGWCKALS TCGSHFAVVI LFFGPCVFNS LRPSTTLPID KMVAVFYTVI TAILNPVIYS LRNAEMRKAM KRLWIRTLRL 

       310 
NEK

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


V M K D       T   L F T D     I L   S I V K      L L  V E Q N  
 F V A   T S P R   L G I   L I Q A   G W W    D S I    V R Q   
I V T Y   L S N   A V I L   F S H   Q A M C  L K P A  I V F C  
 I A T   F V C P   G G N   M F G G   F F L    T A S    F L F   
V P N L   G F F   V S L T   V W A   F F H L  S Y C I  A T Y L  
 S Y I   L I V V   F S I   I G V L   T G G    E M F    L V I   
          A F H   L L V G   V T C   L F I E  S L Y S  L F N G  
         S G C T   Y S A   V Q W N   V T L    L F F    L V I   
          S L A   L I V M           D Y A M  Y M P S  T M V T  
         K C W G   L H L             V Y H                 S   
                      T R           K C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
2-aminoacetophenone - 3.8462 1  grape, sweet, musty
androstenone -4.52 2 0.1983 2  animal, musky
geraniol -2.46 2 1.2152 2  citrus, floral, fruity, rose, sweet, waxy

1.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).

2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
Prot.Sim.Expr.2.53 3.29 3.32 3.33 3.36 3.37 3.40 3.41 4.53 4.56 4.57 4.60 45.49 45.51 45.52 45.53 5.39 5.42 5.43 5.46 5.47 6.48 6.51 6.55 6.59 7.38 7.39 7.41 7.42
OR4X2100 53%Y L L H G G I F G H S Q F D L V I N G L S F C S S A V Y T
OR4X192 23%Y M L H G G A F G H S Q F D V H I N G I S F C Y C A V Y T
OR4K1788 84%L I L H G G M V G H S Q F D L P I N S I S F C Y P A V Y T
OR4F487 92%L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4F587 92%L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4F1787 92%L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4Q286Y L L H G A M F G H S Q F D V P M N S I S F C Y F S V Y N
OR4D585 80%Y L F H G G I F G H S Q Y D V P M N N V T F C Y P S V Y T
OR4L185 11%L M M H G G M T G H S Q F D L P V D S L S F C Y P A V Y T
OR4Q385 92%L I L H G A M F G H S Q Y D V P V N S L S F C Y F S L Y T
OR4S284 57%Y L V H G C I F G H S Q F D V H V N S I A F C Y D A V Y T
OR4D984 100%F M F H G G V F G H S Q Y D V P M N N V S F C Y P S V F T
OR4D1184 34%F I F H G G I F G H S Q Y D V P M N N V T F C Y P S V F T
OR4A4784Y L E H G G V F G H S Q F D M Y V N G A C F C Y P S V Y T
OR4K1484 80%L I L H G G M V G H S Q F D L P M D S L S F C Y P S V Y T
OR10G884 57%F L F H G G C F G H S Q L D A P I T V V A F G Y G A V Y T
OR4K1384 96%L M M H G G M M G H S Q F D L P V D S L S F C Y P S V Y T
OR4K1584 42%V I V H T G M V G H T Q F D L P I D S L S F C Y P A V Y T
OR4E283 96%H L L H A C I F G H S Q F D V P I N S I S F C Y P S V Y T
OR4N583 96%Y L L H G A M F G H S Q F D V P M N S L S F A Y F S L H T
OR4A1683Y L E H G G V F G H S Q V D M Y V N G I C F C Y P T V Y S
OR10G483 88%F L F H G S C F G H S Q F D A P I D I V A F C Y G A I Y T
OR4B182 69%Y I F H G V I L G H S Q F D L Q V N S F S F A Y P A V Y T
OR4C382 34%Y L A H G G I I G H S Q A D L Y V N S I C F C Y P A L Y G
OR4C1282 23%Y A E H G A I I G H A Q M D L Y V N S I C F C Y S A V Y T
OR4N282 73%Y L L H G G G L G H S Q F D V P M N S M T F G Y P S L H T
OR10G682I L F H G C C F G H S Q F D I P T D I L A Y C Y C A V Y T
OR10G782 80%F L F H G S C F G H S Q F D A P I N I V A F G Y G A V Y T
OR10G982 46%F L F H G S C F G H S Q L D A P I D I V A F C Y G A I Y T
OR4D181 100%Y I F H G G V F G H S Q Y D V P M N S L V F C Y P S I Y T
OR4F681F I I H G G M V G H S Q F D L P V N S I S F L Y P A I D A
OR4D681 65%F I F H G G I F G H S Q Y Y V L M N N V T F C Y P S I N T
OR4D1081 96%F M F H G G V F G H S Q Y D V H M N N L T F C Y P S V F T
OR4A1581 15%Y L D H A G V I G H S Q L D L Y M N G I C F C Y P T V L T
OR4P481 57%Y L T H G G I F G H S Q F D V Y V N S I A F A Y V A L Y T
OR4S180 42%Y L A H G G I F G H S Q F D V H V N S I S L P Y S I L N I
OR4K580 61%Q I I H T G M V S H T Q F D L P I N S L S F C Y P A I Y T
OR4M180Y L L H G A M F G H S Q F D I T M S S I S F S Y P S V H T
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