SMILES:
C[C@H]1CC[C@@H]([C@H](C1)O)C(C)C
Aroma Description:
cooling, mentholic, minty1
| Receptor | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|
| OR8K3 | -2.24 4, -5.32 6 | 0.1 4 | currant, plum, mentholic, honey, berry | |
| OR1G1 | - | 5.5838 3 | waxy, tart, orange, sweet, aldehydic, medicinal, citrus, clean, fresh, anise | |
| OR10X1 | -2.72 2 | 0.4009 2 | mentholic | |
| OR2A12 | -1.54 2 | 0.0683 2 | clove, mentholic | |
| OR2J2 | - | 1.1667 4 | tart, carnation, orange, hay, clove, sweet, warm, cinnamon | |
| OR51E1 | - | 0.7 4 | cheesy, sweaty, sour, acidic, rancid | |
| OR52D1 | - | 0.2538 3 | anise, cheesy, rancid, orange, dairy, sour, sweet, tart, sharp, pineapple | |
| OR7D4 | - | 0.2 5 | animal | |
| OR10G3 | - | 0 4 | ||
| OR10J5 | - | 0 4 | ||
| OR11A1 | - | 0 4 | ||
| OR1A1 | - | 0 4 | ||
| OR1C1 | - | 0 4 | ||
| OR2A25 | - | 0 4 | ||
| OR2B11 | - | 0 4 | ||
| OR2J3 | - | 0 4 | ||
| OR2W1 | - | 0 4 | ||
| OR51L1 | - | 0 4 | ||
| OR56A4 | - | 0 4 | ||
| OR5K1 | - | 0 4 | ||
| OR8D1 | - | -0.0367 4 | ||
| OR10G7 | - | -0.0667 4 | ||
| OR5P3 | - | -2.5667 4 |
SMILES:
C[C@H]1CC[C@@H]([C@H](C1)O)C(C)C
Aroma Description:
cooling, mentholic, minty
| Receptor | Docking Score | Correlated Perceptual Qualities |
|---|
1.) The Good Scents Company
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
3.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
4.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821
5.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.
6.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.