Names:
cinnamaldehyde
SMILES:
C1=CC=C(C=C1)/C=C/C=O
Aroma Description:
sweet, spicy, candy, cinnamon, warm1
SMILES:
C1=CC=C(C=C1)/C=C/C=O
Aroma Description:
sweet, spicy, candy, cinnamon, warm
| Receptor | Expr.% | Agonist? | Dock Score | Known agonist | Correlated Perceptual Qualities |
|---|
Dock Score is a measure of how strongly the algorithm thinks the odorant is likely to be an agonist of the receptor.
Receptors in italics are "orphans", i.e. receptors whose agonists have not been identified experimentally.
1.) The Good Scents Company
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
3.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
4.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.
5.) D. Gonzalez-Kristeller, J.B.P. do Nascimento, P.A.F. Galante, B. Malnic, Identification of agonists for a group of human odorant receptors, Front. Pharmacol. 6 (2015)
6.) Fukutani, Y., Koshizawa, T., & Yohda, M. (2021). Application of Vapor Phase Stimulation Method for Screening of Human Odorant Receptors Responding to Cinnamaldehyde. Sensors and Materials, 33(12), 4203-4210.
7.) Reina Kanemaki Kahori Kishigami, Mei Saito, Masafumi Yohda, and Yosuke Fukutani. Harnessing Odorant Receptor Activation to Suppress Real Malodor. Int. J. Mol. Sci. 2025, 26, 1566.