SMILES:
C1=CN=CC=N1
Aroma Description:
pungent, sweet, corn, roasted, hazelnut, barley1
| Receptor | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|
| OR4M1 | - | 10 7 | corn, hazelnut, acacia, pungent, chemical, hawthorn | |
| OR2B3 | -8.61 2 | 0.0638 2 | corn, malty, carnation, hazelnut, pungent, clove, vinegar | |
| OR1G1 | - | 4.0609 3 | waxy, tart, orange, sweet, aldehydic, medicinal, citrus, clean, fresh, anise | |
| OR52D1 | - | 1.3198 3 | anise, cheesy, rancid, orange, dairy, sour, sweet, tart, sharp, pineapple | |
| OR51E1 | - | 0.5 4 | cheesy, sweaty, sour, acidic, rancid | |
| OR7D4 | - | 0.3 5 | animal | |
| OR10G3 | - | 0 4 | ||
| OR10G7 | - | 0 4 | ||
| OR10J5 | - | 0 4 | ||
| OR11A1 | - | 0 4 | ||
| OR1C1 | - | 0 4 | ||
| OR2A25 | - | 0 4 | ||
| OR2J2 | - | 0 4 | ||
| OR2J3 | - | 0 4 | ||
| OR51L1 | - | 0 4 | ||
| OR56A4 | - | 0 4 | ||
| OR5K1 | - | 0 4 | ||
| OR8K3 | - | 0 4 | ||
| OR2W3 | - | 0 6 | ||
| OR8D1 | - | -0.0333 4 | ||
| OR2B11 | - | -0.6667 4 | ||
| OR2W1 | - | -1.3333 4 | ||
| OR1A1 | - | -1.5667 4 | ||
| OR5P3 | - | -1.5667 4 |
SMILES:
C1=CN=CC=N1
Aroma Description:
pungent, sweet, corn, roasted, hazelnut, barley
| Receptor | Docking Score | Correlated Perceptual Qualities |
|---|
1.) The Good Scents Company
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
3.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
4.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821
5.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.
6.) Huang, J., Lam, H., Koziol-White, C., Limjunyawong, N., Kim, D., Kim, N., ... & An, S. S. (2020). The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. Proceedings of the National Academy of Sciences, 117(45), 28485-28495.
7.) Zhao W, Ho L, Varghese M, Yemul S, Dams-O'Connor K, Gordon W, Knable L, Freire D, Haroutunian V, Pasinetti GM. Decreased level of olfactory receptors in blood cells following traumatic brain injury and potential association with tauopathy. J Alzheimers Dis. 2013;34(2):417-429. doi: 10.3233/JAD-121894. PMID: 23241557; PMCID: PMC3968322.