SMILES:
CC(C)(CCCC1=CCC(CC1)C=O)O

Aroma Description:
aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody1

Receptor log10 EC50 Adj. Top Antagonist? Correlated Perceptual Qualities
OR10J5 -5 2, -2.16 4, -3.49 5, -5.14 10 4.4374 2, 3.1667 4, 10 6  cyclamen, watery, cedar, rhubarb
OR10A6 -5.59 9 -  floral, cinnamyl, honey, rhubarb, neroli, hyacinth, cyclamen, balsamic, cinnamon, dirty
OR1G1 - 5.0761 3  waxy, tart, orange, sweet, aldehydic, medicinal, citrus, clean, fresh, anise
OR2W3 - 4.186 8  lemon, citrus
OR6P1 -2.86 2 0.4408 2  hyacinth, honey, cocoa, hawthorn, anise
OR13C4 -2.85 2 0.408 2  (insufficient data)
OR5M9 -2.84 2 0.412 2  (insufficient data)
OR52D1 - 1.269 3  anise, cheesy, rancid, orange, dairy, sour, sweet, tart, sharp, pineapple
OR5K1 - 0.2333 4  hazelnut, nutty, roasted, peanut
OR10G3 - 0 4   
OR10G7 - 0 4   
OR11A1 - 0 4   
OR1C1 - 0 4   
OR2A25 - 0 4   
OR2B11 - 0 4   
OR2J2 - 0 4, 0 5   
OR2J3 - 0 4   
OR2W1 - 0 4, 0 5   
OR51E1 - 0 4, 0 5   
OR51L1 - 0 4, 0 5   
OR56A4 - 0 4   
OR8D1 - 0 4   
OR8K3 - 0 4   
OR2C1 - 0 5   
OR51B4 - 0 7   
OR11H4 - 0 9   
OR2AG2 - 0 9   
OR1A1 - -0.5 4, 0 5   
OR5P3 - -1.3333 4, 0 5   

SMILES:
CC(C)(CCCC1=CCC(CC1)C=O)O

Aroma Description:
aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody

Receptor Docking Score Correlated Perceptual Qualities

1.) The Good Scents Company

2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.

3.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002

4.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821

5.) Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD. Odor coding by a Mammalian receptor repertoire. Sci Signal. 2009 Mar 3;2(60):ra9. doi: 10.1126/scisignal.2000016. PMID: 19261596; PMCID: PMC2774247.

6.) Tong, T., Ryu, S., Min, Y. et al. Olfactory receptor 10J5 responding to α-cedrene regulates hepatic steatosis via the cAMP–PKA pathway. Sci Rep 7, 9471 (2017).

7.) Weber, Lea et al. “Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis.” PloS one vol. 12,3 e0172491. 8 Mar. 2017, doi:10.1371/journal.pone.0172491

8.) Huang, J., Lam, H., Koziol-White, C., Limjunyawong, N., Kim, D., Kim, N., ... & An, S. S. (2020). The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. Proceedings of the National Academy of Sciences, 117(45), 28485-28495.

9.) Duroux R, Mandeau A, Guiraudie-Capraz G, Quesnel Y, Loing E. A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors. Molecules. 2020 Oct 16;25(20):4743. doi: 10.3390/molecules25204743. PMID: 33081083; PMCID: PMC7587601.

10.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.