Names:
gamma-decalactone
SMILES:
CCCCCCC1CCC(=O)O1
Aroma Description:
fresh, oily, waxy, peach, coconut, buttery, sweet1
| Receptor | Expression | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|---|
| OR10A3 | 100 | -5.17 7 | - | peach, coconut, lactonic | |
| OR10A6 | 100 | -4.73 7 | - | peach, coconut, lactonic, sweet | |
| OR1D2 | 100 | -3.75 3 | - | rose, citrus, waxy, fresh, floral, sweet, fatty, lime, bois_de_rose, peach | |
| OR1G1 | 61 | - | 9.4924 2 | waxy, sweet, citrus, tart, fresh, orange, aldehydic, fatty, rose, floral | |
| OR2W1 | 53 | -4.103 5 | - | sweet, fatty, hay, alliaceous, tart, cinnamon, coumarinic, coconut, orange | |
| OR2J2 | 92 | - | (probable agonist) 7, (agonist) 8 | sweet, peach, coconut, tart, carnation, hay, fatty, orange, cinnamon, creamy | |
| OR10J1 | 80 | - | (probable agonist) 7, (agonist) 8 | peach, coconut, lactonic, creamy, buttery | |
| OR2AP1 | ? | - | (agonist) 8 | peach, coconut, apricot, lactonic | |
| OR56A4 | 100 | - | (agonist) 7 | rancid, coconut, fatty, waxy, peach, cloth, laundered, creamy, buttery, cheesy | |
| OR52D1 | 100 | - | 0.203 2 | dairy, cheesy, anise, creamy, peach, sweet, fatty, milky, orange, lactonic | |
| OR5A1 | 100 | - | 0 4 | ||
| OR5A2 | 100 | - | 0 4 | ||
| OR5AN1 | 100 | - | 0 4 | ||
| OR7A17 | 100 | - | 0 6 |
SMILES:
CCCCCCC1CCC(=O)O1
Aroma Description:
fresh, oily, waxy, peach, coconut, buttery, sweet
| Receptor | Expr.% | Agonist? | Dock Score | Known agonist | Correlated Perceptual Qualities |
|---|
Dock Score is a measure of how strongly the algorithm thinks the odorant is likely to be an agonist of the receptor.
Receptors in italics are "orphans", i.e. receptors whose agonists have not been identified experimentally.
1.) The Good Scents Company
2.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
3.) Veithen, A.; Wilin, F.; Philippeau, M.; Chatelain, P. OR1D2 is a broadly tuned human olfactory receptor. Chem. Senses 2015, 40, 262–263.
4.) Keiichi Yoshikawa, Jun Deguchi, Hu Jieying et al. Diverse yet selective tuning of an odorant receptor for sensing four classes of musk compounds, 03 August 2022, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-1916850/v1]
5.) Franziska Haag, Antonella Di Pizio, Dietmar Krautwurst, The key food odorant receptive range of broadly tuned receptor OR2W1. Food Chemistry 375 (2022) 131680
6.) Dan Takase, Tomohiro Shirai, Kensuke Misawa, Hiroaki Matsunami, Keiichi Yoshikawa, An odorant receptor for a key odor constituent of ambergris. Communications Biology | (2025)8:792. doi: 10.1038/s42003-025-08229-y
7.) Roger Emter, Christel Merillat, Fiona Buchli, Felix Flachsmann, Andreas Natsch. Decoding human olfaction by high heterologous expression of odorant receptors detecting signature odorants. Current Biology, October 10, 2025
8.) Roger EmterAndreas Natsch Modified olfactory receptors WO2024126820A1