Olfactory Receptor family 2 subfamily M member 7.
Estimated Expression: 34% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MAWENQTFNS DFLLLGIFNH SPTHTFLFFL VLAIFSVAFM GNSIMVLLIY LDTQLHTPMY FLLSQLSLMD LMLICTTVPK MAFNYLSGSK SISMAGCATQ 110 120 130 140 150 160 170 180 190 200 IFFYISLLGS ECFLLAVMSY DRYTAICHPL RYTNLMRPKI CGLMTAFSWI LGSTDGIIDA VATFSFSYCG SREIAHFCCD FPSLLILSCN DTSIFEEVIF 210 220 230 240 250 260 270 280 290 300 ICCIVMLVFP VAIIITSYAR VILAVIHMGS GEGRRKAFTT CSSHLMVVGM YYGAGLFMCI QPTSHHSPMQ DKMVSVFYTI VTPMLNPLIY SLRNKEVTRA 310 320 LMKILGKGKS GD
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 D Q M P H I S T D T A S I S K L Y T P S H V M K S T P Q E E F V A D I G A M N F A F T H Y F V S I C M I F I V I G D Q T A C M K P V L F F L V I T F L G A I C C T S G L F F I T T C A L V L M P T G Y Y V L M V I W S L S I Y I L M L V S F I L P N M G V V V P F F A T M S G L D M L M F A Y I M L H I I I A L G C L F C E S L Q S I S N G S S C T Y S T I K P R V A L L L F L V M T F A I V R A D Y S M Y M P T L Y I L K R R G V A L T Y R D M H I H C I A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| (S)-(-)-citronellol | -3.85 1 | 9 1 | citrus, fatty, floral, fruity, green, leathery, rose, sweet, terpenic, waxy | |
| methanethiol | - | 10 2 | alliaceous, cabbage, cheesy, creamy, eggy, garlic, meaty, oily, vegetable | |
| geraniol | -3.2 1 | 8 1 | citrus, floral, fruity, rose, sweet, waxy |
1.) Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD. Odor coding by a Mammalian receptor repertoire. Sci Signal. 2009 Mar 3;2(60):ra9. doi: 10.1126/scisignal.2000016. PMID: 19261596; PMCID: PMC2774247.
2.) Pelchat ML, Bykowski C, Duke FF, Reed DR. Excretion and perception of a characteristic odor in urine after asparagus ingestion: a psychophysical and genetic study. Chem Senses. 2011;36(1):9-17. doi:10.1093/chemse/bjq081
| Prot. | Sim. | Expr. | 2.53 | 3.29 | 3.32 | 3.33 | 3.36 | 3.37 | 3.40 | 3.41 | 4.53 | 4.56 | 4.57 | 4.60 | 45.49 | 45.51 | 45.52 | 45.53 | 5.39 | 5.42 | 5.43 | 5.46 | 5.47 | 6.48 | 6.51 | 6.55 | 6.59 | 7.38 | 7.39 | 7.41 | 7.42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR2M7 | 100 | 34% | L | I | Y | I | L | G | C | F | G | D | G | D | C | D | F | P | I | C | C | M | L | Y | G | C | T | S | V | Y | T |
| OR2M5 | 94 | 34% | L | I | Y | V | L | G | C | F | G | D | A | D | F | D | F | P | L | C | C | M | I | Y | G | Y | T | S | V | Y | T |
| OR2M2 | 91 | 100% | L | I | Y | I | S | G | C | F | G | D | G | D | F | E | F | P | I | C | C | M | L | Y | A | Y | T | S | V | Y | T |
| OR2M3 | 90 | 100% | L | I | Y | T | L | G | C | F | G | D | G | D | F | D | F | P | L | C | C | M | I | Y | A | Y | T | S | V | Y | T |
| OR2T12 | 89 | 69% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | A | P | M | C | C | M | L | Y | G | Y | K | S | A | Y | T |
| OR2V2 | 87 | 96% | L | I | F | V | V | G | G | L | G | D | G | Q | F | E | M | L | I | C | C | M | L | Y | A | Y | R | S | I | Y | T |
| OR2T8 | 87 | 96% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | T | P | M | C | C | M | L | Y | A | Y | K | S | A | Y | T |
| OR2T33 | 87 | 92% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | T | P | M | C | C | M | L | Y | A | Y | K | S | A | Y | T |
| OR2M4 | 85 | 96% | L | I | Y | V | L | G | C | F | G | D | G | V | F | D | V | A | L | C | C | M | L | Y | A | Y | A | S | A | Y | T |
| OR2T4 | 84 | 80% | Y | M | Y | V | A | G | F | F | G | D | G | F | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T5 | 84 | 100% | Y | M | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T29 | 84 | 100% | Y | M | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T11 | 84 | 96% | F | I | Y | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | Y | Q | S | A | Y | T |
| OR2V1 | 84 | L | I | F | V | V | G | G | L | G | D | G | Q | F | E | V | Q | L | C | C | M | L | Y | A | Y | R | S | I | Y | T | |
| OR11L1 | 83 | 100% | Y | L | F | V | G | A | C | F | G | T | G | P | F | D | L | P | I | L | S | V | L | Y | M | Y | S | S | V | Y | T |
| OR2T10 | 83 | 92% | Y | M | Y | L | G | G | C | C | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | F | Y | T |
| OR2AG1 | 82 | 100% | F | M | A | L | G | G | D | L | A | S | A | Y | L | E | I | P | V | M | G | F | L | Y | A | Y | S | S | V | Y | T |
| OR2T2 | 81 | Y | I | Y | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | N | H | S | A | Y | T | |
| OR10A6 | 80 | 100% | F | M | I | L | G | G | C | F | G | L | G | Q | S | E | T | P | A | G | T | I | I | Y | A | Y | K | S | L | Y | S |
| OR2T35 | 80 | Y | I | L | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | N | H | S | A | Y | T | |
| OR2T3 | 80 | Y | M | Y | L | A | G | V | F | G | D | G | L | F | E | T | P | M | C | C | M | L | F | S | Y | S | S | A | Y | T | |
| OR5AP2 | 80 | 61% | Y | F | F | G | L | G | C | F | G | N | A | H | Y | D | T | P | I | F | S | I | V | F | I | Y | T | S | V | Y | T |