Olfactory Receptor family 2 subfamily T member 12.
Estimated Expression: 69% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MEMRNTTPDF ILLGLFNHTR AHQVLFMMLL ATVLTSLFSN ALMILLIHWD HRLHRPMYFL LSQLSLMDMM LVSTTVPKMA ADYLTGNKAI SRAGCGVQIF 110 120 130 140 150 160 170 180 190 200 FLPTLGGGEC FLLAAMAYDR YAAVCHPLRY PTLMSWQLCL RMTMSSWLLG AADGLLQAVA TLSFPYCGAH EIDHFFCEAP VLVRLACADT SVFENAMYIC 210 220 230 240 250 260 270 280 290 300 CVLMLLVPFS LILSSYGLIL AAVLLMRSTE ARKKAFATCS SHVAVVGLFY GAGIFTYMRP KSHRSTNHDK VVSAFYTMFT PLLNPLIYSV RNSEVKEALK 310 320 RWLGTCVNLK HQQNEAHRSR
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 D H N T H V S T D T A S I A K L Y A R T H V V K S K P R N E F V A Q L G A R D A A V Q H Y F A S M Y T I Y M A L G D Q V G C M K P V M M F L F M T F I G A V C C A A G L F F I T T S A L L L L P T G Y F L L M L L W S L T P L V L M M T L V T L P N L G V V F P V S M T M G G G D M L F L S Y I A V H L I L S R L C L F C E S L Q S L A N S S S C T Y S S L Q W S A A L L L F L I M A F A L I L G D Y A M Y M P R W H I L K K R A V A A A Y R D M L L H C V A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|
| Prot. | Sim. | Expr. | 2.53 | 3.29 | 3.32 | 3.33 | 3.36 | 3.37 | 3.40 | 3.41 | 4.53 | 4.56 | 4.57 | 4.60 | 45.49 | 45.51 | 45.52 | 45.53 | 5.39 | 5.42 | 5.43 | 5.46 | 5.47 | 6.48 | 6.51 | 6.55 | 6.59 | 7.38 | 7.39 | 7.41 | 7.42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR2T12 | 100 | 69% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | A | P | M | C | C | M | L | Y | G | Y | K | S | A | Y | T |
| OR2T8 | 96 | 96% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | T | P | M | C | C | M | L | Y | A | Y | K | S | A | Y | T |
| OR2T33 | 96 | 92% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | T | P | M | C | C | M | L | Y | A | Y | K | S | A | Y | T |
| OR2M5 | 95 | 34% | L | I | Y | V | L | G | C | F | G | D | A | D | F | D | F | P | L | C | C | M | I | Y | G | Y | T | S | V | Y | T |
| OR2V2 | 94 | 96% | L | I | F | V | V | G | G | L | G | D | G | Q | F | E | M | L | I | C | C | M | L | Y | A | Y | R | S | I | Y | T |
| OR2M2 | 92 | 100% | L | I | Y | I | S | G | C | F | G | D | G | D | F | E | F | P | I | C | C | M | L | Y | A | Y | T | S | V | Y | T |
| OR2M3 | 92 | 100% | L | I | Y | T | L | G | C | F | G | D | G | D | F | D | F | P | L | C | C | M | I | Y | A | Y | T | S | V | Y | T |
| OR2V1 | 91 | L | I | F | V | V | G | G | L | G | D | G | Q | F | E | V | Q | L | C | C | M | L | Y | A | Y | R | S | I | Y | T | |
| OR2M4 | 90 | 96% | L | I | Y | V | L | G | C | F | G | D | G | V | F | D | V | A | L | C | C | M | L | Y | A | Y | A | S | A | Y | T |
| OR2M7 | 90 | 34% | L | I | Y | I | L | G | C | F | G | D | G | D | C | D | F | P | I | C | C | M | L | Y | G | C | T | S | V | Y | T |
| OR2T4 | 89 | 80% | Y | M | Y | V | A | G | F | F | G | D | G | F | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T5 | 89 | 100% | Y | M | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T11 | 89 | 96% | F | I | Y | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | Y | Q | S | A | Y | T |
| OR2T29 | 89 | 100% | Y | M | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T10 | 88 | 92% | Y | M | Y | L | G | G | C | C | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | F | Y | T |
| OR11L1 | 87 | 100% | Y | L | F | V | G | A | C | F | G | T | G | P | F | D | L | P | I | L | S | V | L | Y | M | Y | S | S | V | Y | T |
| OR10A3 | 86 | 100% | F | M | I | L | G | G | C | F | G | V | A | Q | F | E | T | P | A | G | T | I | V | Y | A | Y | K | S | L | Y | T |
| OR2AG1 | 86 | 100% | F | M | A | L | G | G | D | L | A | S | A | Y | L | E | I | P | V | M | G | F | L | Y | A | Y | S | S | V | Y | T |
| OR2T35 | 86 | Y | I | L | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | N | H | S | A | Y | T | |
| OR2T2 | 85 | Y | I | Y | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | N | H | S | A | Y | T | |
| OR10A2 | 84 | F | M | F | F | G | V | C | F | G | V | A | Q | F | D | S | P | A | G | T | V | V | Y | L | Y | K | S | L | Y | T | |
| OR10AD1 | 84 | 100% | F | M | V | F | G | V | C | I | G | N | G | L | F | E | A | P | I | D | A | V | I | Y | A | Y | H | S | L | Y | T |
| OR2T3 | 84 | Y | M | Y | L | A | G | V | F | G | D | G | L | F | E | T | P | M | C | C | M | L | F | S | Y | S | S | A | Y | T | |
| OR2T6 | 84 | 92% | Y | C | Y | M | M | G | F | F | G | D | S | L | F | E | A | P | M | C | C | M | L | Y | A | Y | Q | S | A | Y | T |
| OR7G1 | 84 | 61% | L | I | V | L | A | G | S | C | S | D | A | Q | F | E | V | V | I | A | S | F | G | Y | A | Y | S | S | V | Y | T |
| OR10A6 | 83 | 100% | F | M | I | L | G | G | C | F | G | L | G | Q | S | E | T | P | A | G | T | I | I | Y | A | Y | K | S | L | Y | S |
| OR2T1 | 83 | 69% | Y | H | Y | L | V | G | F | F | G | D | G | L | F | E | A | P | M | C | C | M | L | Y | A | Y | H | S | V | Y | T |
| OR2T27 | 83 | 96% | Y | H | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | H | S | A | Y | T |
| OR2Z1 | 83 | 84% | C | I | L | T | G | V | G | V | G | N | A | Q | F | E | V | P | L | S | G | I | L | Y | A | Y | C | S | L | Y | S |
| OR7G3 | 83 | F | I | V | L | V | G | N | G | S | D | A | H | F | E | L | A | V | V | T | L | G | Y | G | Y | S | S | V | Y | T | |
| OR10AG1 | 82 | 65% | Y | M | F | L | G | G | C | L | T | V | V | E | F | D | I | P | V | V | A | F | I | F | G | Y | K | S | L | Y | T |
| OR10K2 | 82 | 96% | Y | M | F | L | G | C | S | F | G | V | A | I | F | D | I | A | I | L | C | V | L | Y | A | Y | Q | S | V | Y | T |
| OR10J1 | 82 | 80% | Y | M | F | V | G | I | C | F | G | V | A | Q | F | D | I | R | T | I | S | V | L | Y | A | Y | K | S | V | Y | T |
| OR10J3 | 82 | 26% | Y | L | Y | L | G | I | C | F | G | M | A | Q | F | D | V | R | N | V | S | V | L | Y | A | Y | K | S | V | Y | T |
| OR2D3 | 82 | 100% | F | I | F | L | G | C | C | A | G | V | S | D | F | E | P | P | I | M | G | I | L | Y | G | Y | N | S | V | Y | T |
| OR5A1 | 82 | 100% | Y | F | F | V | G | L | C | L | G | S | S | Q | F | D | L | P | N | V | V | V | G | F | A | Y | S | S | V | Y | S |
| OR10J4 | 81 | Y | L | Y | L | G | V | C | F | G | T | A | Q | F | D | I | R | T | I | S | V | L | Y | T | Y | K | S | V | Y | T | |
| OR10A5 | 81 | 100% | F | M | F | F | G | V | C | F | G | V | A | Q | F | D | S | P | A | G | T | V | V | Y | S | Y | K | S | L | Y | T |
| OR5AR1 | 81 | 53% | Y | F | F | V | V | D | C | Y | G | S | L | H | F | E | I | P | L | L | C | I | E | Y | V | Y | T | S | V | Y | T |
| OR5P2 | 81 | 100% | Y | L | A | A | A | T | C | V | G | I | A | Y | F | D | F | A | L | S | S | I | I | Y | I | Y | N | S | V | Y | T |
| OR5P3 | 81 | 100% | Y | L | V | V | G | T | C | F | G | N | A | F | F | D | Y | S | P | S | S | I | I | Y | I | Y | K | S | V | Y | T |
| OR9I1 | 81 | 96% | Y | F | F | T | A | G | C | F | G | G | A | R | F | D | L | P | I | F | G | V | I | F | L | Y | S | S | V | Y | T |
| OR10P1 | 81 | 80% | Y | M | F | I | G | I | C | C | G | T | A | H | L | D | I | L | V | A | T | F | I | F | A | Y | Q | S | L | Y | T |
| OR2G6 | 81 | 100% | F | L | A | M | G | S | C | I | G | T | S | Q | F | E | V | P | L | A | S | F | L | Y | I | Y | A | S | L | Y | T |
| OR5AP2 | 81 | 61% | Y | F | F | G | L | G | C | F | G | N | A | H | Y | D | T | P | I | F | S | I | V | F | I | Y | T | S | V | Y | T |
| OR10A7 | 80 | 15% | F | M | F | F | G | S | C | F | G | V | S | Q | F | D | G | P | A | S | T | F | I | Y | A | Y | K | S | L | Y | T |
| OR2C1 | 80 | 100% | F | L | F | L | G | A | C | I | G | N | S | Q | L | E | V | P | L | V | C | F | T | Y | A | Y | A | S | L | Y | S |
| OR7A17 | 80 | 100% | F | M | F | V | G | G | S | L | A | N | S | Q | F | E | L | N | M | A | A | L | A | C | G | Y | S | S | V | Y | T |
| OR5V1 | 80 | 96% | Y | L | F | V | V | G | C | L | G | N | S | H | F | D | I | P | L | T | G | I | G | Y | A | Y | I | S | V | Y | S |
| OR4K3 | 80 | L | M | L | H | G | G | I | V | G | H | A | Q | F | D | L | P | M | T | S | I | A | F | C | Y | P | S | V | Y | T |