Olfactory Receptor family 2 subfamily T member 6.
Estimated Expression: 92% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MNENNETLTR GFTLMGLFTH NKCSGFFFGV ICAVFFMAMI ANGVMIFLIN IDPHLHTPMY FLLSHLSVID TLYISTIVPK MLVDYLMGEG TISFIACTAQ 110 120 130 140 150 160 170 180 190 200 CFLYMGFMGA EFFLLGLMAY DRYVAICNPL RYPVLISWRV CWMILASSWF GGALDSFLLT PITMSLPFCA SHQINHFFCE APTMLRLACG DKTTYETVMY 210 220 230 240 250 260 270 280 290 300 VCCVAMLLIP FSVVTASYTR ILITVHQMTS AEGRKKAFAT CSSHMMVVTL FYGAALYTYT LPQSYHTPIK DKVFSAFYTI LTPLLNPLIY SLRNRDVMGA 310 LKRVVARC
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 D K I P Y T T K D T I S I T G L Y C K N H F V K S Q P L T E Y P T L L A I F D V L F G S Y F A S T Y T V Y M V F S D Q A T C M K P V V G F F L I T Y L A A V C C L A G G L F C I T S A C I L L P T G Y F L L M A F W S F G M Y I Y L T M F F V L P N L T V V F P I S A L I A G M D I V I M A Y I M M H T V V S M W C L F F E S L H S V G N A S S C T Y S A V R W S L G L L L F F I M A F A L I R T D Y A M Y M P T I N I L K K R G V T I V Y R D M Q H N C I A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| hydrogen sulfide | - | 6.5217 1 | egg, sulfurous | |
| methanethiol | - | 2.1739 1 | alliaceous, cabbage, cheesy, creamy, eggy, garlic, meaty, oily, vegetable |
| Prot. | Sim. | Expr. | 2.53 | 3.29 | 3.32 | 3.33 | 3.36 | 3.37 | 3.40 | 3.41 | 4.53 | 4.56 | 4.57 | 4.60 | 45.49 | 45.51 | 45.52 | 45.53 | 5.39 | 5.42 | 5.43 | 5.46 | 5.47 | 6.48 | 6.51 | 6.55 | 6.59 | 7.38 | 7.39 | 7.41 | 7.42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR2T6 | 100 | 92% | Y | C | Y | M | M | G | F | F | G | D | S | L | F | E | A | P | M | C | C | M | L | Y | A | Y | Q | S | A | Y | T |
| OR2T5 | 94 | 100% | Y | M | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T29 | 94 | 100% | Y | M | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T11 | 93 | 96% | F | I | Y | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | Y | Q | S | A | Y | T |
| OR2T4 | 93 | 80% | Y | M | Y | V | A | G | F | F | G | D | G | F | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T2 | 89 | Y | I | Y | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | N | H | S | A | Y | T | |
| OR2T27 | 89 | 96% | Y | H | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | H | S | A | Y | T |
| OR2T1 | 89 | 69% | Y | H | Y | L | V | G | F | F | G | D | G | L | F | E | A | P | M | C | C | M | L | Y | A | Y | H | S | V | Y | T |
| OR2T35 | 88 | Y | I | L | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | N | H | S | A | Y | T | |
| OR2T10 | 86 | 92% | Y | M | Y | L | G | G | C | C | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | F | Y | T |
| OR2T3 | 86 | Y | M | Y | L | A | G | V | F | G | D | G | L | F | E | T | P | M | C | C | M | L | F | S | Y | S | S | A | Y | T | |
| OR2V2 | 85 | 96% | L | I | F | V | V | G | G | L | G | D | G | Q | F | E | M | L | I | C | C | M | L | Y | A | Y | R | S | I | Y | T |
| OR2M4 | 85 | 96% | L | I | Y | V | L | G | C | F | G | D | G | V | F | D | V | A | L | C | C | M | L | Y | A | Y | A | S | A | Y | T |
| OR11L1 | 84 | 100% | Y | L | F | V | G | A | C | F | G | T | G | P | F | D | L | P | I | L | S | V | L | Y | M | Y | S | S | V | Y | T |
| OR2M5 | 84 | 34% | L | I | Y | V | L | G | C | F | G | D | A | D | F | D | F | P | L | C | C | M | I | Y | G | Y | T | S | V | Y | T |
| OR2T12 | 84 | 69% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | A | P | M | C | C | M | L | Y | G | Y | K | S | A | Y | T |
| OR10R2 | 83 | 57% | Y | M | F | L | A | I | C | L | G | A | S | V | F | D | I | S | I | C | G | V | L | Y | A | Y | T | T | V | Y | T |
| OR10K2 | 82 | 96% | Y | M | F | L | G | C | S | F | G | V | A | I | F | D | I | A | I | L | C | V | L | Y | A | Y | Q | S | V | Y | T |
| OR2V1 | 82 | L | I | F | V | V | G | G | L | G | D | G | Q | F | E | V | Q | L | C | C | M | L | Y | A | Y | R | S | I | Y | T | |
| OR2M2 | 81 | 100% | L | I | Y | I | S | G | C | F | G | D | G | D | F | E | F | P | I | C | C | M | L | Y | A | Y | T | S | V | Y | T |
| OR10V1 | 81 | 76% | Y | M | F | V | G | G | C | V | G | L | S | L | Y | D | M | P | L | I | S | V | L | Y | T | Y | S | S | V | Y | T |
| OR2T34 | 81 | Y | M | H | L | A | G | V | F | G | D | G | L | F | E | T | P | T | C | C | M | L | F | S | Y | S | S | A | Y | T | |
| OR2M3 | 81 | 100% | L | I | Y | T | L | G | C | F | G | D | G | D | F | D | F | P | L | C | C | M | I | Y | A | Y | T | S | V | Y | T |
| OR2A2 | 81 | Y | T | Y | L | A | V | C | L | G | L | S | H | F | E | I | L | I | T | C | V | L | F | A | Y | D | S | L | H | S | |
| OR2AG1 | 81 | 100% | F | M | A | L | G | G | D | L | A | S | A | Y | L | E | I | P | V | M | G | F | L | Y | A | Y | S | S | V | Y | T |
| OR10W1 | 81 | 100% | Y | M | F | I | G | S | C | F | G | L | S | L | F | D | V | P | V | A | A | A | I | Y | C | Y | S | S | L | Y | T |
| OR2T8 | 80 | 96% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | T | P | M | C | C | M | L | Y | A | Y | K | S | A | Y | T |
| OR2T33 | 80 | 92% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | T | P | M | C | C | M | L | Y | A | Y | K | S | A | Y | T |
| OR2L5 | 80 | Y | S | F | M | A | G | A | L | G | N | S | H | F | D | V | P | V | S | S | F | L | Y | F | Y | R | A | V | Y | T | |
| OR5V1 | 80 | 96% | Y | L | F | V | V | G | C | L | G | N | S | H | F | D | I | P | L | T | G | I | G | Y | A | Y | I | S | V | Y | S |
| OR8J3 | 80 | 96% | N | L | F | L | I | V | V | M | G | T | A | V | Y | D | I | A | V | S | A | N | L | Y | M | Y | Q | S | V | Y | T |
| OR10AC1 | 80 | Y | M | F | V | G | G | C | F | G | V | S | L | F | D | I | T | L | A | C | L | L | Y | A | Y | R | A | L | Y | T | |
| OR5J2 | 80 | 57% | Y | H | F | G | I | T | G | F | G | N | T | H | F | D | I | P | L | F | S | I | A | Y | L | Y | S | S | M | Y | T |